antibody

Goat anti-TAp63alpha / deltaNp63alpha Antibody

MBS422600

0.1 mg

290 USD

polyclonal

goat

nonconjugated

human, mouse, rat, dog, cow

western blot, enzyme immunoassay

Antibody

Goat anti-TAp63alpha / deltaNp63alpha Antibody

TAp63alpha/deltaNp63alpha

TP63; tumor protein p63; AIS; B(p51A); B(p51B); EEC3; KET; LMS; NBP; RHS; SHFM4; TP53CP; TP53L; TP73L; p40; p51; p53CP; p63; p73H; p73L; CUSP; Goat Anti-Trp63 (mouse); TP63; tumor protein p63; AIS; B(p51A); B(p51B); EEC3; KET; LMS; NBP; OFC8; RHS; SHFM4; TP53CP; TP53L; TP73L; p40; p51; p53CP; p63; p73H; p73L; CUSP; OTTHUMP00000209734; OTTHUMP00000209738; OTTHUMP00000209740; OTTHUMP00000209741; OTTHUMP00000209742; amplified in squamous cell carcinoma; chronic ulcerative stomatitis protein; keratinocyte transcription factor KET; transformation-related protein 63; tumor protein 63; tumor protein p53-competing protein; tumor protein p53-like; tumor protein p63 deltaN isoform delta; tumor protein p73-like

tumor protein 63 isoform 1; Tumor protein 63; tumor protein 63; CUSP; transformation-related protein 63; tumor protein p53-competing protein; amplified in squamous cell carcinoma; chronic ulcerative stomatitis protein; keratinocyte transcription factor KET; tumor protein p63 deltaN isoform delta; tumor protein p63; Chronic ulcerative stomatitis protein; CUSP; Keratinocyte transcription factor KET; Transformation-related protein 63; TP63; Tumor protein p73-like; p73L; p40; p51

TP63

TP63; TP63; AIS; KET; LMS; NBP; RHS; p40; p51; p63; EEC3; OFC8; p73H; p73L; SHFM4; TP53L; TP73L; p53CP; TP53CP; B(p51A); B(p51B); KET; P63; P73H; P73L; TP73L; p63; CUSP; TP63; p73L

P63_HUMAN

Polyclonal

Goat

Human, Mouse, Rat, Dog, Pig, Cow

680

RNKQQRIKEEGE

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

100ug specific antibody in 200ul

Aliquot and store at -20 degree C. Minimize freezing and thawing.

Peptide ELISA (EIA), Western Blot (WB)

Western Blot: Approx 75-80kDa band observed in Human, Mouse and Rat Heart lysates (calculated MW of 76.8kDa according to NP_003713.3). Recommended concentration: 0.3-1ug/ml. Peptide ELISA: antibody detection limit dilution 1:32000.

Epitope: C Terminus. Immunogen: Peptide with sequence C-RNKQQRIKEEGE, from the C Terminus of the protein sequence according to NP_003713.3; NP_001108452.1. Corresponding Immunizing Peptide: Catalog #MBS427438

Important Note: This antibody is expected to recognize isoform 1 (NP_003713.3) and isoform 4 (NP_001108452.1) of TP63.

31543818

NP_003713.3

NM_003722.4

65,288 Da

Apoptosis Pathway 198797!!Direct P53 Effectors Pathway 137939!!MicroRNAs In Cancer Pathway 852705!!MicroRNAs In Cancer Pathway 852928!!TP53 Network Pathway 198896

This gene encodes a member of the p53 family of transcription factors. An animal model, p63 -/- mice, has been useful in defining the role this protein plays in the development and maintenance of stratified epithelial tissues. p63 -/- mice have several developmental defects which include the lack of limbs and other tissues, such as teeth and mammary glands, which develop as a result of interactions between mesenchyme and epithelium. Mutations in this gene are associated with ectodermal dysplasia, and cleft lip/palate syndrome 3 (EEC3); split-hand/foot malformation 4 (SHFM4); ankyloblepharon-ectodermal defects-cleft lip/palate; ADULT syndrome (acro-dermato-ungual-lacrimal-tooth); limb-mammary syndrome; Rap-Hodgkin syndrome (RHS); and orofacial cleft 8. Both alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different proteins. Many transcripts encoding different proteins have been reported but the biological validity and the full-length nature of these variants have not been determined. [provided by RefSeq, Jul 2008]

0.1 mg

290 USD