catalog number :
MBS422585
products full name :
Goat anti-BBS4 (aa 33-46) Antibody
products short name :
BBS4
products name syn :
BBS4; Bardet-Biedl syndrome 4; Bardet-Biedl syndrome 4 protein; Goat Anti-BBS4 (aa 125-139); BBS4; Bardet-Biedl syndrome 4; Bardet-Biedl syndrome 4 protein
other names :
Bardet-Biedl syndrome 4 protein isoform 1; Bardet-Biedl syndrome 4 protein; Bardet-Biedl syndrome 4 protein; Bardet-Biedl syndrome 4
products gene name :
BBS4
other gene names :
BBS4; BBS4
uniprot entry name :
BBS4_HUMAN
reactivity :
Human, Mouse, Dog, Pig
sequence :
EKQNWLIHLHYIRK
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Western Blot: Approx 65kDa band observed in Human Testis lysates (calculated MW of 58.3kDa according to NP_149017.2). Recommended concentration: 1-3ug/ml. Peptide ELISA: antibody detection limit dilution 1:1000.
other info1 :
Epitope: Internal Region (Near N Terminus). Immunogen: Peptide with sequence C-EKQNWLIHLHYIRK, from the Internal Region (near N Terminus) of the protein sequence according to NP_149017.2.
other info2 :
Corresponding Immunizing Peptide: Catalog #MBS428337
ncbi acc num :
NP_149017.2
ncbi gb acc num :
NM_033028.4
ncbi mol weight :
38,282 Da
ncbi summary :
This gene is a member of the Bardet-Biedl syndrome (BBS) gene family. Bardet-Biedl syndrome is an autosomal recessive disorder characterized by severe pigmentary retinopathy, obesity, polydactyly, renal malformation and mental retardation. The proteins encoded by BBS gene family members are structurally diverse. The similar phenotypes exhibited by mutations in BBS gene family members are likely due to the protein's shared roles in cilia formation and function. Many BBS proteins localize to the basal bodies, ciliary axonemes, and pericentriolar regions of cells. BBS proteins may also be involved in intracellular trafficking via microtubule-related transport. The protein encoded by this gene has sequence similarity to O-linked N-acetylglucosamine (O-GlcNAc) transferases in plants and archaebacteria and in human forms a multi-protein "BBSome" complex with seven other BBS proteins. Alternative splice variants have been described but their predicted protein products have not been experimentally verified.[provided by RefSeq, Oct 2014]