This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
antibody
product name :
Goat anti-GM2A (aa 179-189) Antibody
catalog :
MBS422556
quantity :
0.1 mg
price :
290 USD
clonality :
polyclonal
host :
goat
conjugate :
nonconjugated
reactivity :
human, mouse, rat, dog
application :
western blot, enzyme immunoassay
product information
catalog number :
MBS422556
products type :
Antibody
products full name :
Goat anti-GM2A (aa 179-189) Antibody
products short name :
GM2A
products name syn :
cerebroside sulfate activator protein; GM2 ganglioside activator; SAP-3; sphingolipid activator protein 3; GM2A; Goat Anti-GM2A (aa 164-175); GM2A; GM2 ganglioside activator; SAP-3; cerebroside sulfate activator protein; sphingolipid activator protein 3
other names :
ganglioside GM2 activator isoform 1; Ganglioside GM2 activator; ganglioside GM2 activator; shingolipid activator protein 3; sphingolipid activator protein 3; cerebroside sulfate activator protein; GM2 ganglioside activator; Cerebroside sulfate activator protein; GM2-AP; Sphingolipid activator protein 3; SAP-3
products gene name :
GM2A
other gene names :
GM2A; GM2A; SAP-3; GM2-AP; SAP-3
uniprot entry name :
SAP3_HUMAN
clonality :
Polyclonal
host :
Goat
reactivity :
Human, Mouse, Rat, Dog
sequence length :
193
sequence :
KRLGCIKIAAS
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Western Blot: In transfected HEK293 transiently expressing full-length Human GM2A (myc and DYKDDDDK tagged), a band of approx. 28kDa was observed. No bands were observed in mock-transfected HEK293 and the same band was observed using anti-DYKDDDDK tag antibody. Approx. 24kDa band was observed in Rat Kidney lysates (calculated MW of 21.5kDa according to NP_758838.2). Recommended concentration: 0.3-1ug/ml. Peptide ELISA: antibody detection limit dilution 1:4000.
other info1 :
Epitope: Internal Region. Immunogen: Peptide with sequence KRLGCIKIAAS, from the internal region of the protein sequence according to NP_000396.2. Corresponding Immunizing Peptide: Catalog #MBS427659
other info2 :
Important Note: This antibody is expected to recognize isoform 1 (NP_000396.2) only.
ncbi gi num :
39995109
ncbi acc num :
NP_000396.2
ncbi gb acc num :
NM_000405.4
ncbi mol weight :
20,838 Da
ncbi pathways :
Glycosphingolipid Metabolism Pathway 530751!!Lysosome Pathway 99052!!Lysosome Pathway 96865!!Metabolism Pathway 477135!!Metabolism Of Lipids And Lipoproteins Pathway 160976!!Sphingolipid Metabolism Pathway 119543
ncbi summary :
This gene encodes a small glycolipid transport protein which acts as a substrate specific co-factor for the lysosomal enzyme beta-hexosaminidase A. Beta-hexosaminidase A, together with GM2 ganglioside activator, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Mutations in this gene result in GM2-gangliosidosis type AB or the AB variant of Tay-Sachs disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2009]
size :
0.1 mg
price :
290 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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