catalog number :
MBS422548
products full name :
Goat anti-ABCC4 (aa70-82) Antibody
products short name :
ABCC4
products name syn :
ABCC4; ATP-binding cassette; sub-family C (CFTR/MRP); member 4; EST170205; MOAT-B; MOATB; MRP4; ATP-binding cassette sub-family C member 4; MRP/cMOAT-related ABC transporter; bA464I2.1 (ATP-binding cassette; sub-family C (CFTR/MRP); member 4); Goat Anti-ABCC4 / MRP4; ATP-binding cassette, sub-family C (CFTR/MRP), member 4; EST170205; MOAT-B; MOATB; MRP4; ATP-binding cassette sub-family C member 4; MRP/cMOAT-related ABC transporter; bA464I2.1 (ATP-binding cassette, sub-family C (CFTR/MRP), member 4); canalicular multispecific organic anion transporter (ABC superfamily); multi-specific organic anion transporter B; multidrug resistance-associated protein 4; multispecific organic anion transporter B
other names :
multidrug resistance-associated protein 4 isoform 1; Multidrug resistance-associated protein 4; multidrug resistance-associated protein 4; MRP/cMOAT-related ABC transporter; multi-specific organic anion transporter B; bA464I2.1 (ATP-binding cassette, sub-family C (CFTR/MRP), member 4); canalicular multispecific organic anion transporter (ABC superfamily); ATP-binding cassette, sub-family C (CFTR/MRP), member 4; ATP-binding cassette sub-family C member 4; MRP/cMOAT-related ABC transporter; Multi-specific organic anion transporter B; MOAT-B
products gene name :
ABCC4
other gene names :
ABCC4; ABCC4; MRP4; MOATB; MOAT-B; MRP4; MOAT-B
uniprot entry name :
MRP4_HUMAN
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Western Blot: Approx 100kDa band observed in Human Lung and Human Prostate lysates (calculated MW of 96.8kDa according to NP_001098985.1). Recommended concentration: 0.3-1ug/ml. Peptide ELISA: antibody detection limit dilution 1:64000.
other info1 :
Epitope: N Terminus (near). Immunogen: Peptide with sequence RAENDAQKPSLTR-C, from the N Terminus (near) of the protein sequence according to NP_005836.2; NP_001098985.1. Corresponding Immunizing Peptide: Catalog #MBS427474
other info2 :
Important Note: This antibody is expected to recognize both reported isoforms (NP_005836.2; NP_001098985.1).
ncbi acc num :
NP_005836.2
ncbi gb acc num :
NM_005845.4
ncbi mol weight :
96,841 Da
ncbi pathways :
ABC Transporters Pathway 83035!!ABC Transporters Pathway 436!!ABC-family Proteins Mediated Transport Pathway 106573!!Bile Secretion Pathway 193146!!Bile Secretion Pathway 193095!!Drug Induction Of Bile Acid Pathway 698755!!Fluoropyrimidine Activity Pathway 198778!!Hemostasis Pathway 106028!!Platelet Activation, Signaling And Aggregation Pathway 106034!!Platelet Degranulation Pathway 106050
ncbi summary :
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This family member plays a role in cellular detoxification as a pump for its substrate, organic anions. It may also function in prostaglandin-mediated cAMP signaling in ciliogenesis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2014]