catalog number :
MBS422542
products full name :
Goat anti-Aspa (mouse) Antibody
products short name :
Aspa
products name syn :
Aspa; aspartoacylase; RP23-213I10.1; Acy-2;; Acy2; nur7; OTTMUSP00000006437; aminoacylase 2; aminoacylase-2; small lethargic; aspartoacylase; RP23-213I10.1; Acy-2,; Acy2; nur7; OTTMUSP00000006437; aminoacylase 2; aminoacylase-2; aspartoacylase (aminoacylase) 2; small lethargic
other names :
aspartoacylase; Aspartoacylase; aspartoacylase; aminoacylase-2; aspartoacylase (aminoacylase) 2; aspartoacylase; Aminoacylase-2; ACY-2
products gene name :
ASPA
other gene names :
Aspa; Aspa; Acy2; nur7; Acy-2; ACY-2
uniprot entry name :
ACY2_MOUSE
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Western Blot: Approx 35kDa band observed in Mouse and Rat Kidney lysates (calculated MW of 35.3kDa according to NP_075602.2). Recommended concentration: 0.01-0.03ug/ml. Peptide ELISA: antibody detection limit dilution 1:8000.
other info1 :
Epitope: C Terminus. Immunogen: Peptide with sequence C-TLSAKSIRSTLH, from the C Terminus of the protein sequence according to NP_075602.2.
other info2 :
Corresponding Immunizing Peptide: Catalog #MBS427494
ncbi acc num :
NP_075602.2
ncbi gb acc num :
NM_023113.5
ncbi mol weight :
35,345 Da
ncbi pathways :
Alanine And Aspartate Metabolism Pathway 198303!!Alanine, Aspartate And Glutamate Metabolism Pathway 101155!!Alanine, Aspartate And Glutamate Metabolism Pathway 100063!!Histidine Metabolism Pathway 83158!!Histidine Metabolism Pathway 324!!Metabolic Pathways 132962
ncbi summary :
This gene encodes an enzyme that deacteylates N-acetyl-L-aspartic acid (NAA) in the brain to yield acetate and L-aspartate. In humans, alterations in neuronal NAA concentration are associated with many neurodegenerative diseases (decrease associated with epilepsy, multiple sclerosis, myotrophic lateral sclerosis, and Alzheimer's disease; increase associated with Canavan disease). In mouse, mutations in this gene, which cause accumulation of NAA, result in demyelination and spongy degeneration in the CNS and serve as a pathophysiological model for Canavan disease. [provided by RefSeq, Dec 2012]