catalog number :
MBS422538
products full name :
Goat anti-galectin-1 (mouse) (aa100-112) Antibody
products short name :
galectin-1
products name syn :
Goat Anti-galectin-1 (mouse) Antibody; Lgals1; lectin, galactose binding, soluble 1; AA410090; Gal-1; Galbp; L-14.5; L14; Lect14; galectin-1; 14 kDa lectin; S-Lac lectin 1; beta-galactoside binding protein; beta-galactoside-binding lectin L-14-I; galaptin; galectin-1; lactose-binding lectin 1; Lgals1 antibody; lectin; galactose binding; soluble 1 antibody; AA410090 antibody; Gal-1 antibody; Galbp antibody; L-14.5 antibody; L14 antibody; Lect14 antibody; galectin-1 antibody; S-Lac lectin 1 antibody; beta-galactoside binding protein antibody; beta-galactoside-binding lectin L-14-I antibody; galaptin antibody; galectin-1 antibody; lactose-binding lectin 1 antibody; Galectin-1; galectin-1 (mouse) (aa100-112)
other names :
galectin-1; Galectin-1; galectin-1; lectin, galactose binding, soluble 1; 14 kDa lectin; Beta-galactoside-binding lectin L-14-I; Galaptin; Lactose-binding lectin 1; Lectin galactoside-binding soluble 1; S-Lac lectin 1
products gene name :
Lgals1
other gene names :
Lgals1; Lgals1; L14; Gal-1; Galbp; L-14.5; Lect14; AA410090; galectin-1; Gbp; Gal-1
uniprot entry name :
LEG1_MOUSE
reactivity :
Tested: Rat; Expected from sequence similarity: Human, Mouse, Rat, Cow
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Peptide ELISA: Antibody detection limit dilution 1: 32000. Western Blot: Approx 15kDa band observed in Rat Pancreas lysates (calculated MW of 14.9kDa according to mouse NP_032521.1 and to rat NP_063969.1). Recommended concentration: 0.5-2ug/ml.
other info1 :
Immunogen: Peptide with sequence C-KLPDGHEFKFPNR, from the internal region of the protein sequence according to NP_032521.1. Epitope: Internal region
ncbi acc num :
NP_032521.1
ncbi gb acc num :
NM_008495.2
ncbi mol weight :
14,866 Da
ncbi pathways :
PodNet: Protein-protein Interactions In The Podocyte Pathway (755428); XPodNet - Protein-protein Interactions In The Podocyte Expanded By STRING Pathway (755427)
uniprot summary :
galectin-1: May regulate apoptosis, cell proliferation and cell differentiation. Binds beta-galactoside and a wide array of complex carbohydrates. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase. Homodimer. Binds LGALS3BP. Interacts with CD2, CD3, CD4, CD7, CD43 and CD45. Interacts with laminin (via poly-N- acetyllactosamine). Expressed in placenta, maternal decidua and fetal membranes. Within placenta, expressed in trophoblasts, stromal cells, villous endothelium, syncytiotrophoblast apical membrane and villous stroma. Within fetal membranes, expressed in amnion, chorioamniotic mesenchyma and chorion. Expressed in cardiac, smooth, and skeletal muscle, neurons, thymus, kidney and hematopoietic cells. Protein type: Secreted; Cell adhesion; Extracellular matrix. Cellular Component: cell surface; cytoplasm; extracellular matrix; extracellular region; extracellular space; intracellular; nucleus; proteinaceous extracellular matrix. Molecular Function: carbohydrate binding; galactose binding; glycoprotein binding; lactose binding; laminin binding; protein binding; protein homodimerization activity; signal transducer activity. Biological Process: apoptosis; heterophilic cell adhesion; maintenance of protein localization; myoblast differentiation; plasma cell differentiation; positive regulation of erythrocyte aggregation; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of virion penetration into host cell; signal transduction; T cell costimulation