product summary
Loading...
company name :
MyBioSource
product type :
antibody
product name :
Goat anti-BBC3 Antibody
catalog :
MBS422523
quantity :
0.1 mg
price :
290 USD
clonality :
polyclonal
host :
goat
conjugate :
nonconjugated
reactivity :
human
application :
western blot, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS422523
products type :
Antibody
products full name :
Goat anti-BBC3 Antibody
products short name :
BBC3
products name syn :
BCL2 binding component 3; Bcl-2 binding component 3; JFY1; PUMA; BBC3; BBC3; BCL2 binding component 3; JFY1; PUMA; Bcl-2 binding component 3
other names :
bcl-2-binding component 3 isoform 1; Bcl-2-binding component 3; bcl-2-binding component 3; p53 up-regulated modulator of apoptosis; BCL2 binding component 3; JFY-1; p53 up-regulated modulator of apoptosis
products gene name :
BBC3
other gene names :
BBC3; BBC3; JFY1; PUMA; JFY-1; PUMA
uniprot entry name :
BBC3B_HUMAN
clonality :
Polyclonal
host :
Goat
reactivity :
Human
sequence length :
261
sequence :
DGGRPQRTVR
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Western Blot: Approx 24kDa band observed in Human peripheral blood mononucleocytes lysates (calculated MW of 26.5kDa according to NP_001120712.1). Recommended concentration: 0.1-0.3ug/ml. Peptide ELISA: antibody detection limit dilution 1:16000.
other info1 :
Epitope: Internal Region. Immunogen: Peptide with sequence C-DGGRPQRTVR, from the internal region of the protein sequence according to NP_001120712.1. Corresponding Immunizing Peptide: Catalog #MBS427491
other info2 :
Important Note: This antibody is expected to recognize isoform 1 (NP_001120712.1) only.
ncbi gi num :
187829730
ncbi acc num :
NP_001120712.1
ncbi gb acc num :
NM_001127240.2
ncbi mol weight :
20,532 Da
ncbi pathways :
Activation Of BH3-only Proteins Pathway 105658!!Activation Of PUMA And Translocation To Mitochondria Pathway 105661!!Apoptosis Pathway 198797!!Apoptosis Pathway 105648!!Apoptosis Modulation And Signaling Pathway 198822!!BH3-only Proteins Associate With And Inactivate Anti-apoptotic BCL-2 Members Pathway 105664!!DNA Damage Response Pathway 198788!!DNA Damage Response (only ATM Dependent) Pathway 198827!!Direct P53 Effectors Pathway 137939!!Hippo Signaling Pathway 749777
ncbi summary :
This gene encodes a member of the BCL-2 family of proteins. This family member belongs to the BH3-only pro-apoptotic subclass. The protein cooperates with direct activator proteins to induce mitochondrial outer membrane permeabilization and apoptosis. It can bind to anti-apoptotic Bcl-2 family members to induce mitochondrial dysfunction and caspase activation. Because of its pro-apoptotic role, this gene is a potential drug target for cancer therapy and for tissue injury. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2011]
size :
0.1 mg
price :
290 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

Would you like to receive email and e-newsletter from MyBioSource about new products, special offers and events? Please click here to join our Mailing List!