catalog number : 
MBS422519
products full name : 
Goat anti-CSF1R (aa734-744) Antibody
products short name : 
CSF1R (aa734-744)
products name syn : 
CD115; CD115 antigen; C-FMS; colony stimulating factor 1 receptor; CSFR; FIM2; FMS; FMS proto-oncogene; macrophage colony stimulating factor I receptor; McDonough feline sarcoma viral (v-fms) oncogene homolog; CSF1R; Goat Anti-CSF1R (aa 700-710); CSF1R; colony stimulating factor 1 receptor; C-FMS; CD115; CSFR; FIM2; FMS; CD115 antigen; FMS proto-oncogene; McDonough feline sarcoma viral (v-fms) oncogene homolog; macrophage colony stimulating factor I receptor
other names : 
macrophage colony-stimulating factor 1 receptor; Macrophage colony-stimulating factor 1 receptor; macrophage colony-stimulating factor 1 receptor; CD115 antigen; CSF-1 receptor; FMS proto-oncogene; proto-oncogene c-Fms; macrophage colony stimulating factor I receptor; McDonough feline sarcoma viral (v-fms) oncogene homolog; colony stimulating factor 1 receptor; CSF-1 receptor (EC:2.7.10.1); CSF-1-R; CSF-1R; M-CSF-R; Proto-oncogene c-Fms; CD_antigen: CD115
products gene name : 
CSF1R
other gene names : 
CSF1R; CSF1R; FMS; CSFR; FIM2; HDLS; C-FMS; CD115; CSF-1R; M-CSF-R; FMS; CSF-1-R; CSF-1R; M-CSF-R
uniprot entry name : 
CSF1R_HUMAN
reactivity : 
Human, Rat, Dog, Cow
purity : 
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form : 
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration : 
100ug specific antibody in 200ul
storage stability : 
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application : 
Peptide ELISA (EIA), Western Blot (WB-Trf)
app notes : 
Western Blot: In transfected HEK293 transiently expressing full-length Human CSF1R (myc and DYKDDDDK tagged), a band of approx. 200kDa was observed. No bands were observed in mock-transfected HEK293 and the same band was observed using anti-myc tag antibody. Recommended concentration, 0.2-1ug/ml.  Peptide ELISA: antibody detection limit dilution 1:8000.
other info1 : 
Epitope: Internal Region.  Immunogen: Peptide with sequence C-NDSFSEQDLDK, from the internal region of the protein sequence according to NP_005202.2.
other info2 : 
Corresponding Immunizing Peptide:  Catalog #MBS427616
ncbi acc num : 
NP_005202.2
ncbi gb acc num : 
NM_005211.3
ncbi mol weight : 
33,248 Da
ncbi pathways : 
C-MYB Transcription Factor Network Pathway  138073!!Cytokine-cytokine Receptor Interaction Pathway  83051!!Cytokine-cytokine Receptor Interaction Pathway  460!!Endocytosis Pathway  102279!!Endocytosis Pathway  102181!!Hematopoietic Cell Lineage Pathway  83078!!Hematopoietic Cell Lineage Pathway  489!!Integrins In Angiogenesis Pathway  137999!!Osteoclast Differentiation Pathway  193147!!Osteoclast Differentiation Pathway  193096
ncbi summary : 
The protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]