catalog number :
MBS422518
products full name :
Goat anti-SNAP23 (aa 135-144) Antibody
products short name :
SNAP23
products name syn :
HsT17016; OTTHUMP00000161263; SNAP23A; SNAP23B; synaptosomal-associated protein 23; synaptosomal-associated protein; 23kDa; SNAP23; Goat Anti-SNAP23; SNAP23; synaptosomal-associated protein, 23kDa; HsT17016; SNAP23A; SNAP23B; OTTHUMP00000161263; synaptosomal-associated protein 23
other names :
synaptosomal-associated protein 23 isoform SNAP23A; Synaptosomal-associated protein 23; synaptosomal-associated protein 23; synaptosomal-associated protein, 23kD; vesicle-membrane fusion protein SNAP-23; synaptosomal-associated protein, 23kDa; Vesicle-membrane fusion protein SNAP-23
products gene name :
SNAP23
other gene names :
SNAP23; SNAP23; SNAP-23; SNAP23A; SNAP23B; HsT17016; SNAP-23
uniprot entry name :
SNP23_HUMAN
reactivity :
Human, Mouse, Rat, Dog, Cow, Rabbit
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Western Blot: Approx 20+26kDa bands observed in Human Peripheral Blood Mononucleocytes lysates (calculated MW of 17.8kDa according to NP_570710.1 and of 23.4kDa according to NP_003816.2). Recommended concentration: 0.2-0.6ug/ml. Peptide ELISA: antibody detection limit dilution 1:2000.
other info1 :
Epitope: C Terminus. Immunogen: Peptide with sequence C-TDKADTNRDR, from the C Terminus of the protein sequence according to NP_003816.2; NP_570710.1. Corresponding Immunizing Peptide: Catalog #MBS427993
other info2 :
Important Note: This antibody is expected to recognize both isoforms (NP_003816.2; NP_570710.1). Amino acid numbering in name refers to NP_003816.2 sequence.
ncbi acc num :
NP_003816.2
ncbi gb acc num :
NM_003825.3
ncbi mol weight :
17,789 Da
ncbi pathways :
Clathrin Derived Vesicle Budding Pathway 119545!!Insulin Signaling Pathway 198845!!Membrane Trafficking Pathway 106160!!Platelet Activation Pathway 952858!!SNARE Interactions In Vesicular Transport Pathway 83057!!SNARE Interactions In Vesicular Transport Pathway 467!!Translocation Of GLUT4 To The Plasma Membrane Pathway 685554!!Trans-Golgi Network Vesicle Budding Pathway 106165
ncbi summary :
Specificity of vesicular transport is regulated, in part, by the interaction of a vesicle-associated membrane protein termed synaptobrevin/VAMP with a target compartment membrane protein termed syntaxin. These proteins, together with SNAP25 (synaptosome-associated protein of 25 kDa), form a complex which serves as a binding site for the general membrane fusion machinery. Synaptobrevin/VAMP and syntaxin are believed to be involved in vesicular transport in most, if not all cells, while SNAP25 is present almost exclusively in the brain, suggesting that a ubiquitously expressed homolog of SNAP25 exists to facilitate transport vesicle/target membrane fusion in other tissues. The protein encoded by this gene is structurally and functionally similar to SNAP25 and binds tightly to multiple syntaxins and synaptobrevins/VAMPs. It is an essential component of the high affinity receptor for the general membrane fusion machinery and is an important regulator of transport vesicle docking and fusion. Two alternative transcript variants encoding different protein isoforms have been described for this gene. [provided by RefSeq, Jul 2008]