Goat anti-IDH1 (aa65-77) Antibody | MyBioSource MBS422516 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

MyBioSource

product type :

antibody

product name :

Goat anti-IDH1 (aa65-77) Antibody

catalog :

MBS422516

quantity :

0.1 mg

price :

290 USD

clonality :

polyclonal

host :

goat

conjugate :

nonconjugated

reactivity :

human, mouse, rat, dog, cow

application :

western blot, enzyme immunoassay

product information

catalog number :

MBS422516

products type :

Antibody

products full name :

Goat anti-IDH1 (aa65-77) Antibody

products short name :

IDH1

products name syn :

IDCD; IDH; IDP; IDPC; isocitrate dehydrogenase 1 (NADP+); soluble; NADP+-specific ICDH; NADP-dependent isocitrate dehydrogenase; cytosolic; NADP-dependent isocitrate dehydrogenase; peroxisomal; OTTHUMP00; OTTHUMP00000206464; OTTHUMP00000206465; PICD; IDH1; Goat Anti-IDH1 (aa153-164); IDH1; isocitrate dehydrogenase 1 (NADP+), soluble; IDCD; IDH; IDP; IDPC; PICD; NADP+-specific ICDH; NADP-dependent isocitrate dehydrogenase, cytosolic; NADP-dependent isocitrate dehydrogenase, peroxisomal; OTTHUMP00000206464; OTTHUMP00000206465; OTTHUMP00000206466; oxalosuccinate decarboxylase

other names :

isocitrate dehydrogenase; Isocitrate dehydrogenase [NADP] cytoplasmic; isocitrate dehydrogenase [NADP] cytoplasmic; isocitrate dehydrogenase [NADP] cytoplasmic; NADP(+)-specific ICDH; oxalosuccinate decarboxylase; epididymis luminal protein 216; epididymis secretory protein Li 26; NADP-dependent isocitrate dehydrogenase, cytosolic; NADP-dependent isocitrate dehydrogenase, peroxisomal; isocitrate dehydrogenase 1 (NADP+), soluble; Cytosolic NADP-isocitrate dehydrogenase; IDP; NADP(+)-specific ICDH; Oxalosuccinate decarboxylase

products gene name :

IDH1

other gene names :

IDH1; IDH1; IDH; IDP; IDCD; IDPC; PICD; HEL-216; HEL-S-26; PICD; IDH

uniprot entry name :

IDHC_HUMAN

clonality :

Polyclonal

host :

Goat

reactivity :

Human, Mouse, Rat, Dog, Cow, Sheep

sequence length :

414

sequence :

KKHNVGVKCATIT

purity :

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

form :

Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

concentration :

100ug specific antibody in 200ul

storage stability :

Aliquot and store at -20 degree C. Minimize freezing and thawing.

tested application :

Peptide ELISA (EIA), Western Blot (WB)

app notes :

Western Blot: Approx 40+45kDa bands observed in lysates of cell line HepG2 and 40kDa in Mouse and Rat Liver lysates (calculated MW of 46.7kDa according to NP_005887.2). The observed 40kDa is consistent with observaton with different antibodies from other commerical sources. Recommended concentration: 1-3ug/ml. Peptide ELISA: antibody detection limit dilution 1:1000.

other info1 :

Epitope: Internal Region. Immunogen: Peptide with sequence KKHNVGVKCATIT, from the internal region of the protein sequence according to NP_005887.2.

other info2 :

Corresponding Immunizing Peptide: Catalog #MBS427589

ncbi gi num :

28178825

ncbi acc num :

NP_005887.2

ncbi gb acc num :

NM_005896.3

ncbi mol weight :

46,659 Da

ncbi pathways :

2-Oxocarboxylic Acid Metabolism Pathway 714485!!2-Oxocarboxylic Acid Metabolism Pathway 717400!!Abnormal Conversion Of 2-oxoglutarate To 2-hydroxyglutarate Pathway 771598!!Biosynthesis Of Amino Acids Pathway 790012!!Biosynthesis Of Amino Acids Pathway 795174!!Carbon Metabolism Pathway 814926!!Carbon Metabolism Pathway 817567!!Citrate Cycle (TCA Cycle) Pathway 82927!!Citrate Cycle (TCA Cycle) Pathway 288!!Citrate Cycle (TCA Cycle, Krebs Cycle) Pathway 855811

ncbi summary :

Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the cytoplasm and peroxisomes. It contains the PTS-1 peroxisomal targeting signal sequence. The presence of this enzyme in peroxisomes suggests roles in the regeneration of NADPH for intraperoxisomal reductions, such as the conversion of 2, 4-dienoyl-CoAs to 3-enoyl-CoAs, as well as in peroxisomal reactions that consume 2-oxoglutarate, namely the alpha-hydroxylation of phytanic acid. The cytoplasmic enzyme serves a significant role in cytoplasmic NADPH production. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Sep 2013]

size :

0.1 mg

price :

290 USD