catalog number :
MBS422510
products full name :
Goat anti-PTCHD1 Antibody
products short name :
PTCHD1
products name syn :
FLJ30296; MGC149798; patched domain containing 1; PTCHD1; PTCHD1; patched domain containing 1; FLJ30296; MGC149798
other names :
patched domain-containing protein 1; Patched domain-containing protein 1; patched domain-containing protein 1; patched domain containing 1
products gene name :
PTCHD1
other gene names :
PTCHD1; PTCHD1
uniprot entry name :
PTHD1_HUMAN
reactivity :
Human, Mouse, Rat, Dog, Cow
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Western Blot: Approx 100kDa band observed in Human Brain (Cerebellum) lysates (calculated MW of 101kDa according to NP_775766.2). Recommended concentration: 0.5-2ug/ml.
An additional band of unknown identity was also consistently observed at 50kDa. This band was successfully blocked by incubation with the immunizing peptide. Peptide ELISA: antibody detection limit dilution 1:16000.
other info1 :
Epitope: Internal Region. Immunogen: Peptide with sequence C-DFQKTSRVSER, from the internal region of the protein sequence according to NP_775766.2.
other info2 :
Corresponding Immunizing Peptide: Catalog #MBS427529
ncbi acc num :
NP_775766.2
ncbi gb acc num :
NM_173495.2
ncbi mol weight :
28,889 Da
ncbi summary :
This gene encodes a membrane protein with a patched domain. The encoded protein is similar to Drosophila proteins which act as receptors for the morphogen sonic hedgehog. Deletions in this gene, which is located on the X chromosome, are associated with intellectual disability and autism (PMID: 21091464, PMID: 20844286). [provided by RefSeq, Aug 2011]