This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
antibody
product name :
Goat anti-ALDH5A1 (aa 485-496) Antibody
catalog :
MBS422470
quantity :
0.1 mg
price :
290 USD
clonality :
polyclonal
host :
goat
conjugate :
nonconjugated
reactivity :
human, mouse, rat, dog, cow
application :
western blot, immunohistochemistry, enzyme immunoassay
product information
catalog number :
MBS422470
products type :
Antibody
products full name :
Goat anti-ALDH5A1 (aa 485-496) Antibody
products short name :
ALDH5A1
products name syn :
aldehyde dehydrogenase 5 family; member A1; aldehyde dehydrogenase 5A1; mitochondrial succinate semialdehyde dehydrogenase; NAD(+)-dependent succinic semialdehyde dehydrogenase; SSADH; SSDH; succinate-semialdehyde dehydrogenase; ALDH5A1; Goat Anti-ALDH5A1 (aa 301-312); aldehyde dehydrogenase 5 family, member A1; SSADH; SSDH; NAD(+)-dependent succinic semialdehyde dehydrogenase; aldehyde dehydrogenase 5A1; mitochondrial succinate semialdehyde dehydrogenase; succinate-semialdehyde dehydrogenase
other names :
succinate-semialdehyde dehydrogenase, mitochondrial isoform 1; Succinate-semialdehyde dehydrogenase, mitochondrial; succinate-semialdehyde dehydrogenase, mitochondrial; aldehyde dehydrogenase 5 family member A1; mitochondrial succinate semialdehyde dehydrogenase; NAD(+)-dependent succinic semialdehyde dehydrogenase; aldehyde dehydrogenase 5 family, member A1; Aldehyde dehydrogenase family 5 member A1; NAD(+)-dependent succinic semialdehyde dehydrogenase
products gene name :
ALDH5A1
other gene names :
ALDH5A1; ALDH5A1; SSDH; SSADH; SSADH
uniprot entry name :
SSDH_HUMAN
clonality :
Polyclonal
host :
Goat
reactivity :
Human, Mouse, Rat, Dog, Cow
sequence length :
548
sequence :
SQDPAQIWRVAE
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
app notes :
Immunohistochemistry: In paraffin embedded Human Liver shows heavy textured cystoplasm staining in hepatocytes, consistent with mitochondia. Recommended concentration, 5-10ug/ml. Western Blot: Approx 55kDa band observed in Human Liver lysates (calculated MW of 58.7kDa according to NP_733936.1). Recommended concentration: 0.3-1ug/ml. Peptide ELISA: antibody detection limit dilution 1:32000.
other info1 :
Epitope: Internal Region. Immunogen: Peptide with sequence C-SQDPAQIWRVAE, from the internal region of the protein sequence according to NP_733936.1; NP_001071.1. Corresponding Immunizing Peptide: Catalog #MBS428576
other info2 :
Important Note: This antibody is expected to recognize both reported isoforms (NP_733936.1; NP_001071.1). Amino acid numbering in name calculated from NP_733936.1.
ncbi gi num :
25777721
ncbi acc num :
NP_733936.1
ncbi gb acc num :
NM_170740.1
ncbi mol weight :
58,653 Da
ncbi pathways :
Alanine, Aspartate And Glutamate Metabolism Pathway 101142!!Alanine, Aspartate And Glutamate Metabolism Pathway 100063!!Butanoate Metabolism Pathway 83007!!Butanoate Metabolism Pathway 391!!Degradation Of GABA Pathway 187177!!GABA (gamma-Aminobutyrate) Shunt Pathway 413433!!GABA (gamma-Aminobutyrate) Shunt Pathway 468220!!GABA Synthesis, Release, Reuptake And Degradation Pathway 187174!!Metabolic Pathways 132956!!Neuronal System Pathway 106513
ncbi summary :
This protein belongs to the aldehyde dehydrogenase family of proteins. This gene encodes a mitochondrial NAD(+)-dependent succinic semialdehyde dehydrogenase. A deficiency of this enzyme, known as 4-hydroxybutyricaciduria, is a rare inborn error in the metabolism of the neurotransmitter 4-aminobutyric acid (GABA). In response to the defect, physiologic fluids from patients accumulate GHB, a compound with numerous neuromodulatory properties. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
size :
0.1 mg
price :
290 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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