catalog number :
MBS422455
products full name :
Goat anti-CYPOR Antibody
products short name :
CYPOR
products name syn :
CPR; CYPOR; cytochrome P450 reductase; DKFZp686G04235; FLJ26468; NADPH-dependent cytochrome P450 reductase; P450 (cytochrome) oxidoreductase; P450R; POR; POR; P450 (cytochrome) oxidoreductase; CPR; CYPOR; DKFZp686G04235; FLJ26468; P450R; NADPH-dependent cytochrome P450 reductase; cytochrome P450 reductase
other names :
NADPH--cytochrome P450 reductase; NADPH--cytochrome P450 reductase; NADPH--cytochrome P450 reductase; NADPH-dependent cytochrome P450 reductase; P450 (cytochrome) oxidoreductase
other gene names :
POR; POR; CPR; CYPOR; P450R; CYPOR; CPR; P450R
uniprot entry name :
NCPR_HUMAN
reactivity :
Human, Mouse, Rat, Dog, Cow, Pig, Rabbit
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Western Blot: Approx 90kDa band observed in Human, Mouse and Rat Liver lysates (calculated MW of 77.0kDa according to NP_000932.3). Recommended concentration: 0.1-0.3ug/ml. Peptide ELISA: antibody detection limit dilution 1:16000.
other info1 :
Epitope: Internal Region. Immunogen: Peptide with sequence C-TNPPRTNVLYE, from the internal region of the protein sequence according to NP_000932.3.
other info2 :
Corresponding Immunizing Peptide: Catalog #MBS427337
ncbi acc num :
NP_000932.3
ncbi gb acc num :
NM_000941.2
ncbi mol weight :
76,690 Da
ncbi pathways :
1,25-dihydroxyvitamin D3 Biosynthesis Pathway 545291!!1,25-dihydroxyvitamin D3 Biosynthesis Pathway 138457!!Bile Acid Biosynthesis, Neutral Pathway 545316!!Bile Acid Biosynthesis, Neutral Pathway 138622!!Cytochrome P450 Pathway 198773!!Melatonin Degradation I Pathway 545356!!Melatonin Degradation I Pathway 545637!!Superpathway Of Melatonin Degradation 545640!!Superpathway Of Melatonin Degradation 545359
ncbi summary :
This gene encodes an endoplasmic reticulum membrane oxidoreductase with an FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in this gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome. [provided by RefSeq, Jul 2008]