catalog number :
MBS422439
products full name :
Goat anti-KIF26B Antibody
products short name :
KIF26B
products name syn :
KIF26B; kinesin family member 26B; FLJ10157; MGC35030; FLJ10157 antibody; kinesin family member 26B antibody; MGC35030 antibody; KIF26B antibody
other names :
kinesin-like protein KIF26B; Kinesin-like protein KIF26B; kinesin-like protein KIF26B; kinesin family member 26B
products gene name :
KIF26B
other gene names :
KIF26B; KIF26B
uniprot entry name :
KI26B_HUMAN
reactivity :
Expected from sequence similarity: Human, Mouse, Rat, Dog, Cow
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA)
app notes :
Peptide ELISA: Antibody detection limit dilution 1: 16000. Western Blot: Preliminary experiments in Human Brain (Cerebellum), Heart and Liver lysates gave no specific signal but low background (at antibody concentration up to 2ug/ml).
other info1 :
Immunogen: Peptide with sequence SHYECLSLER, from the internal region of the protein sequence according to NP_060482.2. Epitope: Internal region
ncbi acc num :
NP_060482.2
ncbi gb acc num :
NM_018012.3
ncbi mol weight :
184,420 Da
ncbi pathways :
COPI-dependent Golgi-to-ER Retrograde Traffic Pathway (1383042); Factors Involved In Megakaryocyte Development And Platelet Production Pathway (1269377); Golgi-to-ER Retrograde Transport Pathway (1383041); Hemostasis Pathway (1269340); Intra-Golgi And Retrograde Golgi-to-ER Traffic Pathway (1383038); Kinesins Pathway (1269378); Membrane Trafficking Pathway (1269877); Vesicle-mediated Transport Pathway (1269876)
uniprot summary :
KIF26B: Essential for embryonic kidney development. Plays an important role in the compact adhesion between mesenchymal cells adjacent to the ureteric buds, possibly by interacting with MYH10. This could lead to the establishment of the basolateral integrity of the mesenchyme and the polarized expression of ITGA8, which maintains the GDNF expression required for further ureteric bud attraction. Belongs to the kinesin-like protein family. KIF26 subfamily. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Motor; Microtubule-binding. Chromosomal Location of Human Ortholog: 1q44. Cellular Component: cytoplasm; kinesin complex; microtubule. Molecular Function: ATP binding; microtubule binding; plus-end-directed microtubule motor activity. Biological Process: axon guidance; cytoskeleton-dependent intracellular transport; establishment of cell polarity; metabolic process; microtubule-based movement; positive regulation of cell-cell adhesion; protein localization