antibody

Goat anti-SNAP23 Antibody

MBS422433

0.1 mg

290 USD

polyclonal

goat

nonconjugated

human, mouse, rat, cow

western blot, enzyme immunoassay

Antibody

Goat anti-SNAP23 Antibody

SNAP23

HsT17016; OTTHUMP00000161263; SNAP23A; SNAP23B; synaptosomal-associated protein 23; synaptosomal-associated protein; 23kDa; SNAP23; Goat Anti-SNAP23 (aa 135-144); SNAP23; synaptosomal-associated protein, 23kDa; HsT17016; SNAP23A; SNAP23B; OTTHUMP00000161263; synaptosomal-associated protein 23

synaptosomal-associated protein 23 isoform SNAP23A; Synaptosomal-associated protein 23; synaptosomal-associated protein 23; synaptosomal-associated protein, 23kD; vesicle-membrane fusion protein SNAP-23; synaptosomal-associated protein, 23kDa; Vesicle-membrane fusion protein SNAP-23

SNAP23

SNAP23; SNAP23; SNAP-23; SNAP23A; SNAP23B; HsT17016; SNAP-23

SNP23_HUMAN

Polyclonal

Goat

Human, Mouse, Rat, Cow

211

QIKRITDKAD

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

100ug specific antibody in 200ul

Aliquot and store at -20 degree C. Minimize freezing and thawing.

Peptide ELISA (EIA), Western Blot (WB)

Western Blot: Approx 26kDa band observed in Human Placenta lysates (calculated MW of 23.4kDa according to NP_003816.2). The observed molecular weight corresponds to earlier findings with different antibodies from other commercial sources. Recommended concentration: 0.1-0.3ug/ml. Peptide ELISA: antibody detection limit dilution 1:8000.

Epitope: Internal Region. Immunogen: Peptide with sequence C-QIKRITDKAD, from the internal region of the protein sequence according to NP_003816.2; NP_570710.1. Corresponding Immunizing Peptide: Catalog #MBS427350

Important Note: This antibody is expected to recognize both reported isoforms (NP_003816.2; NP_570710.1).

18765729

NP_003816.2

NM_003825.3

17,789 Da

Clathrin Derived Vesicle Budding Pathway 119545!!Insulin Signaling Pathway 198845!!Membrane Trafficking Pathway 106160!!Platelet Activation Pathway 952858!!SNARE Interactions In Vesicular Transport Pathway 83057!!SNARE Interactions In Vesicular Transport Pathway 467!!Translocation Of GLUT4 To The Plasma Membrane Pathway 685554!!Trans-Golgi Network Vesicle Budding Pathway 106165

Specificity of vesicular transport is regulated, in part, by the interaction of a vesicle-associated membrane protein termed synaptobrevin/VAMP with a target compartment membrane protein termed syntaxin. These proteins, together with SNAP25 (synaptosome-associated protein of 25 kDa), form a complex which serves as a binding site for the general membrane fusion machinery. Synaptobrevin/VAMP and syntaxin are believed to be involved in vesicular transport in most, if not all cells, while SNAP25 is present almost exclusively in the brain, suggesting that a ubiquitously expressed homolog of SNAP25 exists to facilitate transport vesicle/target membrane fusion in other tissues. The protein encoded by this gene is structurally and functionally similar to SNAP25 and binds tightly to multiple syntaxins and synaptobrevins/VAMPs. It is an essential component of the high affinity receptor for the general membrane fusion machinery and is an important regulator of transport vesicle docking and fusion. Two alternative transcript variants encoding different protein isoforms have been described for this gene. [provided by RefSeq, Jul 2008]

0.1 mg

290 USD