catalog number :
MBS422355
products full name :
Goat anti-CLCN2 Antibody
products short name :
CLCN2
products name syn :
chloride channel 2; CIC-2; CLC2; ECA2; ECA3; EGI11; EGI3; EGMA; EJM6; EJM8; Epilepsy; idiopathic generalized; susceptibility to; CLCN2; CLCN2; chloride channel 2; CIC-2; CLC2; ECA2; ECA3; EGI11; EGI3; EGMA; EJM6; EJM8; Epilepsy, idiopathic generalized, susceptibility to
other names :
chloride channel protein 2 isoform 1; Chloride channel protein 2; chloride channel protein 2; chloride channel 2; chloride channel, voltage-sensitive 2
products gene name :
CLCN2
other gene names :
CLCN2; CLCN2; CLC2; ECA2; ECA3; EGI3; EGMA; EJM6; EJM8; CIC-2; EGI11; LKPAT; clC-2; ClC-2
uniprot entry name :
CLCN2_HUMAN
reactivity :
Human, Mouse, Rat, Dog, Cow, Rabbit
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Western Blot: Approx 100kDa band observed in lysates of cell line HeLa (calculated MW of 98.5kDa according to NP_004357.3). Recommended concentration: 0.3-1ug/ml. Peptide ELISA: antibody detection limit dilution 1:64000.
other info1 :
Epitope: Internal Region. Immunogen: Peptide with sequence QQLDEPVNFSDCK, from the internal region of the protein sequence according to NP_004357.3. Corresponding Immunizing Peptide: Catalog #MBS428212
other info2 :
Important Note: This antibody is expected to recognize all reported isoforms (NP_004357.3; NP_001164558.1; NP_001164559.1; NP_001164560.1).
ncbi acc num :
NP_004357.3
ncbi gb acc num :
NM_004366.5
ncbi mol weight :
95,399 Da
ncbi pathways :
Ion Channel Transport Pathway 187193!!Mineral Absorption Pathway 212237!!Mineral Absorption Pathway 212220!!Stimuli-sensing Channels Pathway 771568!!Transmembrane Transport Of Small Molecules Pathway 106572
ncbi summary :
This gene encodes a voltage-gated chloride channel. The encoded protein is a transmembrane protein that maintains chloride ion homeostasis in various cells. Defects in this gene may be a cause of certain epilepsies. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2012]