catalog number :
MBS422349
products full name :
Goat anti-WFDC2 (aa29-43) Antibody
products short name :
WFDC2
products name syn :
WFDC2; WAP four-disulfide core domain 2; EDDM4; HE4; MGC57529; WAP5; dJ461P17. 6; WAP domain containing protein HE4-V4; epididymal protein 4; epididymal secretory protein E4; epididymis-specific, whey-acidic protein type, four-disulfide core; major epididy; dJ461P17. 6 antibody; EDDM4 antibody; epididymal protein 4 antibody; epididymal secretory protein E4 antibody; epididymis-specific; whey-acidic protein type; four-disulfide core antibody; HE4 antibody; major epididy antibody; MGC57529 antibody; WAP domain containing protein HE4-V4 antibody; WAP four-disulfide core domain 2 antibody; WAP5 antibody; WFDC2 antibody; WFDC2 (aa29-43)
other names :
WAP four-disulfide core domain protein 2; WAP four-disulfide core domain protein 2; WAP four-disulfide core domain protein 2; WAP four-disulfide core domain 2; Epididymal secretory protein E4; Major epididymis-specific protein E4; Putative protease inhibitor WAP5
products gene name :
WFDC2
other gene names :
WFDC2; WFDC2; HE4; WAP5; EDDM4; dJ461P17.6; HE4; WAP5
uniprot entry name :
WFDC2_HUMAN
reactivity :
Tested: Human; Expected from sequence similarity: Human, Dog
sequence :
GAEKTGVCPELQADQ
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB-Trf)
app notes :
Peptide ELISA: Antibody detection limit dilution 1: 16000. Western Blot: In transfected HEK293 transiently expressing full-length Human WFDC2 (myc and DYKDDDDK tagged), a band of approx.25kDa was observed. No bands were observed in mock-transfected HEK293 and the same band was observed using anti-myc tag antibody. Recommended concentration, 0.2-1ug/ml.
other info1 :
Immunogen: Peptide with sequence GAEKTGVCPELQADQ, from the internal region of the protein sequence according to NP_006094.3. Epitope: Internal region
ncbi acc num :
NP_006094.3
ncbi gb acc num :
NM_006103.3
ncbi mol weight :
11,043 Da
ncbi summary :
This gene encodes a protein that is a member of the WFDC domain family. The WFDC domain, or WAP Signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. This gene is expressed in pulmonary epithelial cells, and was also found to be expressed in some ovarian cancers. The encoded protein is a small secretory protein, which may be involved in sperm maturation. [provided by RefSeq, Jul 2008]
uniprot summary :
WFDC2: a protein that is a member of the WFDC domain family. The WFDC domain, or WAP Signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. This gene is expressed in pulmonary epithelial cells, and was also found to be expressed in some ovarian cancers. The encoded protein is a small secretory protein, which may be involved in sperm maturation. [provided by RefSeq, Jul 2008]. Protein type: Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 20q13.12. Cellular Component: extracellular space. Molecular Function: aspartic-type endopeptidase inhibitor activity; cysteine protease inhibitor activity; endopeptidase inhibitor activity; serine-type endopeptidase inhibitor activity. Biological Process: proteolysis; spermatogenesis