catalog number :
MBS422348
products full name :
Goat anti-MUC16/CA125 Antibody
products short name :
MUC16/CA125
products name syn :
MUC16; mucin 16, cell surface associated; CA125; FLJ14303; CA125 ovarian cancer antigen; mucin 16; CA125 antibody; CA125 ovarian cancer antigen antibody; FLJ14303 antibody; mucin 16 antibody; mucin 16; cell surface associated antibody; MUC16 antibody; MUC16 / CA125
other names :
mucin-16; Mucin-16; mucin-16; mucin 16, cell surface associated; Ovarian cancer-related tumor marker CA125
products gene name :
MUC16
products gene name syn :
CA125
other gene names :
MUC16; MUC16; CA125; CA-125
uniprot entry name :
MUC16_HUMAN
reactivity :
Expected from sequence similarity: Human
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA)
app notes :
Peptide ELISA: Antibody detection limit dilution 1: 16000. Western Blot: Not yet tested - our routinely used western blotting protocol does not allow detection of proteins as large as the calculated size of 1519kDa according to NP_078966.2. Therefore we cannot recommend an optimal concentration and the antibody is an aspiring product.
other info1 :
Immunogen: Peptide with sequence C-PQNLSIRGEYQIN, from the C Terminus of the protein sequence according to NP_078966.2. Epitope: C Terminus
ncbi acc num :
NP_078966.2
ncbi gb acc num :
NM_024690.2
ncbi mol weight :
1,519,175 Da
ncbi pathways :
Defective C1GALT1C1 Causes Tn Polyagglutination Syndrome (TNPS) Pathway (1383050); Defective GALNT12 Causes Colorectal Cancer 1 (CRCS1) Pathway (1383052); Defective GALNT3 Causes Familial Hyperphosphatemic Tumoral Calcinosis (HFTC) Pathway (1383051); Disease Pathway (1268854); Diseases Associated With O-glycosylation Of Proteins Pathway (1383049); Diseases Of Glycosylation Pathway (1269010); Metabolism Of Proteins Pathway (1268677); O-linked Glycosylation Pathway (1268734); O-linked Glycosylation Of Mucins Pathway (1268736); Post-translational Protein Modification Pathway (1268701)
uniprot summary :
MUC16: Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. Protein type: Membrane protein, integral; Membrane protein, peripheral; Cell adhesion. Chromosomal Location of Human Ortholog: 19p13.2. Cellular Component: extracellular space; extrinsic to membrane; Golgi lumen; integral to membrane; plasma membrane; vesicle. Molecular Function: protein binding. Biological Process: cell adhesion; O-glycan processing