Goat anti-Stabilin 1 Antibody | MyBioSource MBS422313 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Goat anti-Stabilin 1 Antibody

catalog :

MBS422313

quantity :

0.1 mg

price :

300 USD

clonality :

polyclonal

host :

goat

conjugate :

nonconjugated

reactivity :

human, dog, cow

application :

immunohistochemistry, enzyme immunoassay

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS422313

products type :

Antibody

products full name :

Goat anti-Stabilin 1 Antibody

products short name :

Stabilin 1

products name syn :

STAB1; stabilin 1; CLEVER-1; FEEL-1; FELE-1; FEX1; KIAA0246; STAB-1; MS-1 antigen; common lymphatic endothelial and vascular endothelial receptor-1; fasciclin egf-like, laminin-type egf-like, and link domain-containing scavenger receptor-1; CLEVER-1 antibody; common lymphatic endothelial and vascular endothelial receptor-1 antibody; fasciclin egf-like; laminin-type egf-like; and link domain-containing scavenger receptor-1 antibody; FEEL-1 antibody; FELE-1 antibody; FEX1 antibody; KIAA0246 antibody; MS-1 antigen antibody; STAB-1 antibody; stabilin 1 antibody; STAB1 antibody; Stabilin 1; Stabilin 1

other names :

stabilin-1; Stabilin-1; stabilin-1; stabilin 1; Fasciclin, EGF-like, laminin-type EGF-like and link domain-containing scavenger receptor 1; FEEL-1; MS-1 antigen

products gene name :

STAB1

other gene names :

STAB1; STAB1; FEX1; FEEL-1; FELE-1; SCARH2; STAB-1; CLEVER-1; FEEL1; KIAA0246; FEEL-1

uniprot entry name :

STAB1_HUMAN

clonality :

Polyclonal

host :

Goat

reactivity :

Tested: Human; Expected from sequence similarity: Human, Dog, Cow, Pig

sequence length :

2570

sequence :

DFPDTQRILTVK

purity :

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

form :

Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

concentration :

100ug specific antibody in 200ul

storage stability :

Aliquot and store at -20 degree C. Minimize freezing and thawing.

tested application :

Peptide ELISA (EIA), Immunohistochemistry (IHC)

app notes :

Peptide ELISA: Antibody detection limit dilution 1: 8000. Immunohistochemistry: In paraffin embedded Human Spleen shows endothelial staining. Recommended concentration, 3-5ug/ml.

other info1 :

Immunogen: Peptide with sequence C-DFPDTQRILTVK, from the C Terminus of the protein sequence according to NP_055951.2. Epitope: C Terminus

ncbi gi num :

61743978

ncbi acc num :

NP_055951.2

ncbi gb acc num :

NM_015136.2

ncbi mol weight :

87,026 Da

ncbi pathways :

Binding And Uptake Of Ligands By Scavenger Receptors Pathway (1269897); Scavenging By Class H Receptors Pathway (1269902); Vesicle-mediated Transport Pathway (1269876)

ncbi summary :

This gene encodes a large, transmembrane receptor protein which may function in angiogenesis, lymphocyte homing, cell adhesion, or receptor scavenging. The protein contains 7 fasciclin, 16 epidermal growth factor (EGF)-like, and 2 laminin-type EGF-like domains as well as a C-type lectin-like hyaluronan-binding Link module. The protein is primarily expressed on sinusoidal endothelial cells of liver, spleen, and lymph node. The receptor has been shown to endocytose ligands such as low density lipoprotein, Gram-positive and Gram-negative bacteria, and advanced glycosylation end products. Supporting its possible role as a scavenger receptor, the protein rapidly cycles between the plasma membrane and early endosomes. [provided by RefSeq, Jul 2008]

uniprot summary :

STAB1: Acts as a scavenger receptor for acetylated low density lipoprotein. Binds to both Gram-positive and Gram-negative bacteria and may play a role in defense against bacterial infection. When inhibited in endothelial tube formation assays, there is a marked decrease in cell-cell interactions, suggesting a role in angiogenesis. Involved in the delivery of newly synthesized CHID1/SI-CLP from the biosynthetic compartment to the endosomal/lysosomal system. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Receptor, misc.; Membrane protein, integral. Chromosomal Location of Human Ortholog: 3p21.1. Cellular Component: integral to plasma membrane; plasma membrane. Molecular Function: calcium ion binding; hyaluronic acid binding; low-density lipoprotein binding; low-density lipoprotein receptor activity; protein binding; protein disulfide oxidoreductase activity; scavenger receptor activity. Biological Process: cell adhesion; cell-cell signaling; defense response to bacterium; inflammatory response; negative regulation of angiogenesis; receptor-mediated endocytosis

size1 :

0.1 mg

price1 :

300 USD

more info or order :

MyBioSource product webpage