product summary
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company name :
MyBioSource
product type :
antibody
product name :
Goat anti-Aconitase 2 Antibody
catalog :
MBS422308
quantity :
0.1 mg
price :
300 USD
clonality :
polyclonal
host :
goat
conjugate :
nonconjugated
reactivity :
human, mouse, rat, dog, cow
application :
western blot, immunohistochemistry, immunocytochemistry, enzyme immunoassay
more info or order :
product information
catalog number :
MBS422308
products type :
Antibody
products full name :
Goat anti-Aconitase 2 Antibody
products short name :
Aconitase 2
products name syn :
Goat Anti-Aconitase 2, Biotinlyated Antibody; ACO2; aconitase 2, mitochondrial; ACONM; MGC20605; MGC33908; aconitate hydratase; citrate hydro-lyase; aconitase 2; mitochondrial antibody; ACONM antibody; MGC20605 antibody; MGC33908 antibody; ACO2 antibody; Aconitase 2; Aconitase 2
other names :
aconitate hydratase, mitochondrial; Aconitate hydratase, mitochondrial; aconitate hydratase, mitochondrial; aconitase 2; Citrate hydro-lyase
products gene name :
ACO2
other gene names :
ACO2; ACO2; ICRD; OCA8; OPA9; ACONM; HEL-S-284; Aconitase
uniprot entry name :
ACON_HUMAN
clonality :
Polyclonal
host :
Goat
reactivity :
Tested: Human; Expected from sequence similarity: Human, Mouse, Rat, Dog, Cow, Pig
sequence length :
780
sequence :
QHVDVSPTSQRLQ
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB), Immunofluorescence (IF), Immunohistochemistry (IHC)
app notes :
Peptide ELISA: Antibody detection limit dilution 1: 32000. Immunohistochemistry: In paraffin embedded Human Breast shows mitochondrial staining in the epithelial cells of the ducts. Recommended concentration, 3-5ug/ml. Western Blot: Approx 90kDa band observed in Human Heart lysates (calculated MW of 85.4kDa according to NP_001089.1). Recommended concentration: 0.01-0.03ug/ml. Immunofluorescence: Customer finds weak pixulate staining in the cytoplasm of HeLa.
other info1 :
Immunogen: Peptide with sequence C-QHVDVSPTSQRLQ, from the internal region of the protein sequence according to NP_001089.1. Epitope: Internal region
ncbi gi num :
4501867
ncbi acc num :
NP_001089.1
ncbi gb acc num :
NM_001098.2
ncbi mol weight :
85,425 Da
ncbi pathways :
2-Oxocarboxylic Acid Metabolism Pathway (714485); 2-Oxocarboxylic Acid Metabolism Pathway (717400); Biosynthesis Of Amino Acids Pathway (790012); Biosynthesis Of Amino Acids Pathway (795174); Carbon Metabolism Pathway (814926); Carbon Metabolism Pathway (817567); Citrate Cycle (TCA Cycle) Pathway (82927); Citrate Cycle (TCA Cycle) Pathway (288); Citrate Cycle (TCA Cycle, Krebs Cycle) Pathway (855811); Citrate Cycle (TCA Cycle, Krebs Cycle) Pathway (468202)
ncbi summary :
The protein encoded by this gene belongs to the aconitase/IPM isomerase family. It is an enzyme that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step of the TCA cycle. This protein is encoded in the nucleus and functions in the mitochondrion. It was found to be one of the mitochondrial matrix proteins that are preferentially degraded by the serine protease 15(PRSS15), also known as Lon protease, after oxidative modification. [provided by RefSeq, Jul 2008]
uniprot summary :
ACO2: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate. Monomer. Belongs to the aconitase/IPM isomerase family. Protein type: Carbohydrate Metabolism - glyoxylate and dicarboxylate; Carbohydrate Metabolism - citrate (TCA) cycle; Mitochondrial; Lyase; EC 4.2.1.3. Chromosomal Location of Human Ortholog: 22q13.2. Cellular Component: mitochondrial matrix; mitochondrion; myelin sheath; nucleus. Molecular Function: 3 iron, 4 sulfur cluster binding; 4 iron, 4 sulfur cluster binding; aconitate hydratase activity; iron ion binding. Biological Process: citrate metabolic process; generation of precursor metabolites and energy; isocitrate metabolic process; tricarboxylic acid cycle. Disease: Infantile Cerebellar-retinal Degeneration; Optic Atrophy 8
size1 :
0.1 mg
price1 :
300 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
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