product summary
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company name :
MyBioSource
product type :
antibody
product name :
Goat anti-LAIR1 Antibody
catalog :
MBS422300
quantity :
0.1 mg
price :
300 USD
clonality :
polyclonal
host :
goat
conjugate :
nonconjugated
reactivity :
human
application :
western blot, enzyme immunoassay
more info or order :
product information
catalog number :
MBS422300
products type :
Antibody
products full name :
Goat anti-LAIR1 Antibody
products short name :
LAIR1
products name syn :
LAIR1; leukocyte-associated immunoglobulin-like receptor 1; CD305; LAIR-1; leukocyte-associated Ig-like receptor 1; CD305 antibody; LAIR-1 antibody; leukocyte-associated Ig-like receptor 1 antibody; leukocyte-associated immunoglobulin-like receptor 1 antibody; LAIR1 antibody
other names :
leukocyte-associated immunoglobulin-like receptor 1 isoform a; Leukocyte-associated immunoglobulin-like receptor 1; leukocyte-associated immunoglobulin-like receptor 1; leukocyte associated immunoglobulin like receptor 1; CD_antigen: CD305
products gene name :
LAIR1
other gene names :
LAIR1; LAIR1; CD305; LAIR-1; CD305; LAIR-1; hLAIR1
uniprot entry name :
LAIR1_HUMAN
clonality :
Polyclonal
host :
Goat
reactivity :
Tested: Human; Expected from sequence similarity: Human
sequence length :
287
sequence :
NDTEDVSQASPSE
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Peptide ELISA: Antibody detection limit dilution 1: 1000. Western Blot: Approx 28kDa band observed in Human Lymph Node lysates (calculated MW of 29.8kDa according to NP_068352.1). Recommended concentration: 1-3ug/ml.
other info1 :
Immunogen: Peptide with sequence C-NDTEDVSQASPSE, from the internal region of the protein sequence according to NP_002278.1; NP_068352.1. Epitope: Internal region
other info2 :
Note: This antibody is expected to recognize both isoforms (NP_002278.1; NP_068352.1).
ncbi gi num :
4504943
ncbi acc num :
NP_002278.1
ncbi gb acc num :
NM_002287.4
ncbi mol weight :
23,049 Da
ncbi pathways :
Adaptive Immune System Pathway (1269171); Immune System Pathway (1269170); Immunoregulatory Interactions Between A Lymphoid And A Non-Lymphoid Cell Pathway (1269201)
ncbi summary :
The protein encoded by this gene is an inhibitory receptor found on peripheral mononuclear cells, including natural killer cells, T cells, and B cells. Inhibitory receptors regulate the immune response to prevent lysis of cells recognized as self. The gene is a member of both the immunoglobulin superfamily and the leukocyte-associated inhibitory receptor family. The gene maps to a region of 19q13.4 called the leukocyte receptor cluster, which contains at least 29 genes encoding leukocyte-expressed receptors of the immunoglobulin superfamily. The encoded protein has been identified as an anchor for tyrosine phosphatase SHP-1, and may induce cell death in myeloid leukemias. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
uniprot summary :
LAIR-1: an inhibitory receptor found on peripheral mononuclear cells, including NK cells, T cells, and B cells. Inhibitory receptors regulate the immune response to prevent lysis of cells recognized as self. The gene is a member of both the immunoglobulin superfamily and the leukocyte-associated inhibitory receptor family. The gene maps to a region called the leukocyte receptor cluster, which contains at least 25 genes encoding leukocyte-expressed receptors of the immunoglobulin superfamily. Protein type: Receptor, misc.; Membrane protein, integral. Chromosomal Location of Human Ortholog: 19q13.4. Cellular Component: integral to membrane; plasma membrane. Molecular Function: protein binding. Biological Process: adaptive immune response; regulation of immune response
size1 :
0.1 mg
price1 :
300 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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