catalog number :
MBS422269
products full name :
Goat anti-Connexin 50 / GJA8 Antibody
products short name :
Connexin 50/GJA8
products name syn :
GJA8; gap junction protein; alpha 8; 50kDa; CAE; CAE1; CX50; CZP1; MP70; OTTHUMP00000025757; connexin 50; gap junction membrane channel protein alpha-8; connexin-50; gap junction alpha-8 protein; lens fiber protein MP70; lens intrinsic membrane protein MP70; GJA8; gap junction protein, alpha 8, 50kDa; CAE; CAE1; CX50; CZP1; MP70; OTTHUMP00000025757; connexin 50; connexin-50; gap junction alpha-8 protein; gap junction membrane channel protein alpha-8; lens fiber protein MP70; lens intrinsic membrane protein MP70
other names :
gap junction alpha-8 protein; Gap junction alpha-8 protein; gap junction alpha-8 protein; connexin 50; connexin-50; lens fiber protein MP70; cell surface glycoprotein; gap junction protein alpha 8 50kDa; lens intrinsic membrane protein MP70; gap junction membrane channel protein alpha-8; gap junction protein, alpha 8, 50kDa; Connexin-50; Cx50; Lens fiber protein MP70
products gene name :
GJA8
other gene names :
GJA8; GJA8; CAE; CAE1; CX50; CZP1; MP70; CTRCT1; Cx50
uniprot entry name :
CXA8_HUMAN
reactivity :
Human, Mouse, Rat, Dog, Cow
sequence :
TPSLCPELTTDDAR
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA)
app notes :
Western Blot: Preliminary experiments in Human Brain (Spinal Cord), Mouse and Rat Eye lysates gave no specific signal but low background (at antibody concentration up to 1ug/ml). Peptide ELISA: antibody detection limit dilution 1:4000.
other info1 :
Epitope: Internal Region. Immunogen: Peptide with sequence TPSLCPELTTDDAR, from the internal region of the protein sequence according to NP_005258.2.
other info2 :
Corresponding Immunizing Peptide: Catalog #MBS427188
ncbi acc num :
NP_005258.2
ncbi gb acc num :
NM_005267.4
ncbi mol weight :
48,229 Da
ncbi pathways :
Calcium Regulation In The Cardiac Cell Pathway 198906!!Gap Junction Assembly Pathway 105928!!Gap Junction Trafficking Pathway 105927!!Gap Junction Trafficking And Regulation Pathway 105926!!Membrane Trafficking Pathway 106160
ncbi summary :
This gene encodes a transmembrane connexin protein that is necessary for lens growth and maturation of lens fiber cells. The encoded protein is a component of gap junction channels and functions in a calcium and pH-dependent manner. Mutations in this gene have been associated with zonular pulverulent cataracts, nuclear progressive cataracts, and cataract-microcornea syndrome. [provided by RefSeq, Dec 2009]