catalog number : 
MBS422268
products full name : 
Goat anti-ATP1B1 Antibody
products short name : 
ATP1B1
products name syn : 
ATP1B1; ATPase; Na+/K+ transporting; beta 1 polypeptide; ATP1B; MGC1798; Beta 1-subunit of Na(+); K(+)-ATPase; Na+/K+ -ATPase beta 1 subunit; Na; K-ATPase beta-1 polypeptide; Na; K-ATPase beta 1 subunit; OTTHUMP00000032537; OTTHUMP00000032538; adenosinetriphosphatase; sodium/potassium-dependent ATPase beta-1 subunit; sodium/potassium-transporting ATPase beta-1 chain; ATPase, Na+/K+ transporting, beta 1 polypeptide; ATP1B; MGC1798; Beta 1-subunit of Na(+),K(+)-ATPase; Na+/K+ -ATPase beta 1 subunit; Na, K-ATPase beta-1 polypeptide; Na,K-ATPase beta 1 subunit; OTTHUMP00000032537; OTTHUMP00000032538; adenosinetriphosphatase; sodium/potassium-dependent ATPase beta-1 subunit; sodium/potassium-transporting ATPase beta-1 chain
other names : 
sodium/potassium-transporting ATPase subunit beta-1; Sodium/potassium-transporting ATPase subunit beta-1; sodium/potassium-transporting ATPase subunit beta-1; adenosinetriphosphatase; sodium pump subunit beta-1; Na, K-ATPase beta-1 polypeptide; Beta 1-subunit of Na(+),K(+)-ATPase; sodium/potassium-dependent ATPase beta-1 subunit; sodium/potassium-transporting ATPase beta-1 chain; sodium-potassium ATPase subunit beta 1 (non-catalytic); ATPase, Na+/K+ transporting, beta 1 polypeptide; Sodium/potassium-dependent ATPase subunit beta-1
products gene name : 
ATP1B1
other gene names : 
ATP1B1; ATP1B1; ATP1B; ATP1B
uniprot entry name : 
AT1B1_HUMAN
reactivity : 
Human, Mouse, Rat, Dog, Cow, Pig
sequence : 
KTEISFRPNDPKSYE
purity : 
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form : 
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration : 
100ug specific antibody in 200ul
storage stability : 
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application : 
Peptide ELISA (EIA), Western Blot (WB)
app notes : 
Western Blot: Approx 48kDa band observed in Rat Retina lysates and 50kDa in Mouse and Rat Kidney lysates (calculated MW of 35.1kDa according to Human NP_001668.1, 35.2kDa according to Mouse NP_033851.1 and Rat NP_037245.2).The observed molecular weight corresponds to the glycosylated form (PMID: 20130120). Recommended concentration: 0.1-0.3ug/ml.  Peptide ELISA: antibody detection limit dilution 1:128000.
other info1 : 
Epitope: Internal Region.  Immunogen: Peptide with sequence C-KTEISFRPNDPKSYE, from the internal region of the protein sequence according to NP_001668.1; NP_001001787.1.  Corresponding Immunizing Peptide:  Catalog #MBS427266
other info2 : 
Important Note: This antibody is expected to recognize both reported isoforms (NP_001668.1; NP_001001787.1).
ncbi acc num : 
NP_001668.1
ncbi gb acc num : 
NM_001677.3
ncbi mol weight : 
34,893 Da
ncbi pathways : 
Adrenergic Signaling In Cardiomyocytes Pathway  908257!!Adrenergic Signaling In Cardiomyocytes Pathway  909696!!Aldosterone-regulated Sodium Reabsorption Pathway  130626!!Aldosterone-regulated Sodium Reabsorption Pathway  130590!!Basigin Interactions Pathway  106065!!Bile Secretion Pathway  193146!!Bile Secretion Pathway  193095!!Calcium Regulation In The Cardiac Cell Pathway  198906!!Carbohydrate Digestion And Absorption Pathway  170720!!Carbohydrate Digestion And Absorption Pathway  170654
ncbi summary : 
The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a beta 1 subunit. Alternatively spliced transcript variants encoding different isoforms have been described, but their biological validity is not known. [provided by RefSeq, Mar 2010]