catalog number :
MBS422264
products full name :
Goat anti-EXT2 Antibody
products short name :
EXT2
products name syn :
EXT2; exostoses (multiple) 2; SOTV; Glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N- acetylglucosaminyltransferase; N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase; exostosin 2; EXT2; exostoses (multiple) 2; SOTV; Glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N- acetylglucosaminyltransferase; N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase; exostosin 2
other names :
exostosin-2 isoform 1; Exostosin-2; exostosin-2; multiple exostoses protein 2; putative tumor suppressor protein EXT2; N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase; glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase; exostosin glycosyltransferase 2; Glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase; Multiple exostoses protein 2; Putative tumor suppressor protein EXT2
products gene name :
EXT2
other gene names :
EXT2; EXT2; SOTV
uniprot entry name :
EXT2_HUMAN
reactivity :
Human, Mouse, Rat, Dog, Cow
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA)
app notes :
Western Blot: Preliminary experiments in lysates of cell line HEK293 gave no specific signal but low background (at antibody concentration up to 1ug/ml). Peptide ELISA: antibody detection limit dilution 1:8000.
other info1 :
Epitope: C Terminus. Immunogen: Peptide with sequence C-PLKVVEHRADPVL, from the C Terminus of the protein sequence according to NP_000392.2; NP_997005.1. Corresponding Immunizing Peptide: Catalog #MBS427184
other info2 :
Important Note: This antibody is expected to recognize isoform 1 and 2 (NP_000392.2; NP_997005.1).
ncbi acc num :
NP_000392.2
ncbi gb acc num :
NM_000401.2
ncbi mol weight :
85,815 Da
ncbi pathways :
Disease Pathway 530764!!Glycogen Storage Diseases Pathway 980468!!Glycosaminoglycan Biosynthesis - Heparan Sulfate / Heparin Pathway 82984!!Glycosaminoglycan Biosynthesis - Heparan Sulfate / Heparin Pathway 358!!Glycosaminoglycan Biosynthesis, Heparan Sulfate Backbone Pathway 413365!!Glycosaminoglycan Biosynthesis, Heparan Sulfate Backbone Pathway 468252!!Glycosaminoglycan Metabolism Pathway 645297!!HS-GAG Biosynthesis Pathway 645306!!Heparan Sulfate/heparin (HS-GAG) Metabolism Pathway 645304!!MPS I - Hurler Syndrome Pathway 685537
ncbi summary :
This gene encodes one of two glycosyltransferases involved in the chain elongation step of heparan sulfate biosynthesis. Mutations in this gene cause the type II form of multiple exostoses. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jul 2008]