product summary
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company name :
MyBioSource
product type :
antibody
product name :
Goat anti-ZYX Antibody
catalog :
MBS422246
quantity :
0.1 mg
price :
290 USD
clonality :
polyclonal
host :
goat
conjugate :
nonconjugated
reactivity :
human, dog
application :
western blot, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS422246
products type :
Antibody
products full name :
Goat anti-ZYX Antibody
products short name :
ZYX
products name syn :
ZYX; zyxin; ESP-2; HED-2
other names :
zyxin; Zyxin; zyxin; zyxin-2; zyxin; Zyxin-2
products gene name :
ZYX
other gene names :
ZYX; ZYX; ESP-2; HED-2
uniprot entry name :
ZYX_HUMAN
clonality :
Polyclonal
host :
Goat
reactivity :
Human, Dog
sequence length :
572
sequence :
QQREKPRVQEKQH
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Western Blot: Approx 85kDa band observed in Human Peripheral Blood Mononucleocytes lysates (calculated MW of 61.3kDa according to NP_003452.1). The observed molecular weight corresponds to earlier findings with different antibodies from other commercial sources. Recommended concentration: 0.1-0.3ug/ml. Peptide ELISA: antibody detection limit dilution 1:4000.
other info1 :
Epitope: Internal Region. Immunogen: Peptide with sequence C-QQREKPRVQEKQH, from the internal region of the protein sequence according to NP_003452.1. Corresponding Immunizing Peptide: Catalog #MBS426068
other info2 :
Important Note: Reported variants represent identical protein: NP_003452.1, NP_001010972.1
ncbi gi num :
4508047
ncbi acc num :
NP_003452.1
ncbi gb acc num :
NM_003461.4
ncbi mol weight :
61,277 Da
ncbi pathways :
E-cadherin Signaling In Keratinocytes Pathway 138002!!Focal Adhesion Pathway 198795!!Focal Adhesion Pathway 83067!!Focal Adhesion Pathway 478!!Integrin-mediated Cell Adhesion Pathway 198816!!Stabilization And Expansion Of The E-cadherin Adherens Junction Pathway 137918
ncbi summary :
Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles. Alternative splicing results in multiple transcript variants that encode the same isoform. [provided by RefSeq, Jul 2008]
size :
0.1 mg
price :
290 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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