catalog number :
MBS422245
products full name :
Goat anti-CLEC16A (aa1040-53) Antibody
products short name :
CLEC16A
products name syn :
Goat Anti-CLEC16A Antibody; CLEC16A; C-type lectin domain family 16, member A; Gop-1; KIAA0350; MGC111457; CLEC16A antibody; C-type lectin domain family 16; member A antibody; Gop-1 antibody; KIAA0350 antibody; MGC111457 antibody; CLEC16A (aa1040-53)
other names :
protein CLEC16A isoform 1; Protein CLEC16A; protein CLEC16A; C-type lectin domain family 16 member A; C-type lectin domain family 16 member A
products gene name :
CLEC16A
other gene names :
CLEC16A; CLEC16A; Gop-1; KIAA0350
uniprot entry name :
CL16A_HUMAN
reactivity :
Tested: Human; Expected from sequence similarity: Human
sequence :
EEAACAEPVGTAED
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Peptide ELISA: Antibody detection limit dilution 1: 1000. Western Blot: Approx.110kDa band observed in Human Kidney and Liver lysates (calculated MW of 118kDa according to NP_056041.1). Recommended concentration: 1-3ug/ml.
other info1 :
Immunogen: Peptide with sequence EEAACAEPVGTAED, from the C Terminus of the protein sequence according to NP_056041.1. Epitope: C Terminus
ncbi acc num :
NP_056041.1
ncbi gb acc num :
NM_015226.2
ncbi mol weight :
14,283 Da
ncbi summary :
This gene encodes a member of the C-type lectin domain containing family. Single nucleotide polymorphisms in introns of this gene have been associated with diabetes mellitus, multiple sclerosis and rheumatoid arthritis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
uniprot summary :
CLEC16A: Insulin-dependent diabetes mellitus is significantly associated with variation within a 233-kb linkage disequilibrium block on chromosome 16p13 that includes KIAA0350. Three common non-coding variants of KIAA0350 in strong linkage disequilibrium reach genome-wide significance for association with the disease (PubMed:17632545). Belongs to the CLEC16A/gop-1 family. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Unknown function. Chromosomal Location of Human Ortholog: 16p13.13. Cellular Component: endosome membrane; lysosomal membrane. Biological Process: autophagy