Goat anti-PRDX1 Antibody | MyBioSource MBS422240 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Goat anti-PRDX1 Antibody

catalog :

MBS422240

quantity :

0.1 mg

price :

305 USD

clonality :

polyclonal

host :

goat

conjugate :

nonconjugated

reactivity :

human, mouse, rat, dog, cow

application :

western blot, enzyme immunoassay

more info or order :

MyBioSource product webpage

image

image 1 :

(0. 01ug/ml) staining of HepG2 lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

image 2 :

(2.5?g/ml) staining of paraffin embedded Human Thyroid Gland. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

image 3 :

(2.5?g/ml) staining of paraffin embedded Human Placenta. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

product information

catalog number :

MBS422240

products type :

Antibody

products full name :

Goat anti-PRDX1 Antibody

products short name :

[PRDX1]

products name syn :

[PRDX1; peroxiredoxin 1; MSP23; NKEFA; PAG; PAGA; PAGB; PRX1; PRXI; TDPX2; natural killer-enhancing factor A; proliferation-associated gene A; thioredoxin-dependent peroxide reductase 2; PRDX1 antibody; peroxiredoxin 1 antibody; MSP23 antibody; NKEFA antibody; PAG antibody; PAGA antibody; PAGB antibody; PRX1 antibody; PRXI antibody; TDPX2 antibody; natural killer-enhancing factor A antibody; proliferation-associated gene A antibody; thioredoxin-dependent peroxide reductase 2 antibody]

other names :

[peroxiredoxin-1; Peroxiredoxin-1; peroxiredoxin-1; peroxiredoxin 1; Natural killer cell-enhancing factor A; NKEF-A; Proliferation-associated gene protein; PAG; Thioredoxin peroxidase 2; Thioredoxin-dependent peroxide reductase 2]

products gene name :

[PRDX1]

other gene names :

[PRDX1; PRDX1; PAG; PAGA; PAGB; PRX1; PRXI; MSP23; NKEFA; TDPX2; NKEF-A; PAGA; PAGB; TDPX2; NKEF-A; PAG]

uniprot entry name :

PRDX1_HUMAN

clonality :

Polyclonal

host :

Goat

reactivity :

Tested: Human; Expected from sequence similarity: Human, Mouse, Rat, Dog, Pig, Cow

sequence length :

199

sequence :

SDPKRTIAQDYG

purity :

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

form :

Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

concentration :

0.5 mg/ml

storage stability :

Aliquot and store at -20 degree C. Minimize freezing and thawing.

tested application :

Peptide ELISA (EIA), Western Blot (WB)

app notes :

Peptide ELISA: Antibody detection limit dilution 1: 32000. Western Blot: Approx.23 to 24kDa band observed in lysates of cell lines HEK293, A431 and HepG2 (calculated MW of 22.1kDa according to NP_859048.1). Recommended concentration: 0.01-0.03ug/ml. IHC: Paraffin embedded Human Thyroid Gland and Placenta. Recommended concentration: 2.5ug/ml.

image1 heading :

Western Blot (WB)

image2 heading :

IHC

image3 heading :

IHC

other info1 :

Immunogen: Peptide with sequence C-SDPKRTIAQDYG, from the internal region of the protein sequence according to NP_859048.1.

other info2 :

Note: Reported variants represent identical protein (NP_002565.1, NP_859047.1, NP_859048.1).

ncbi gi num :

32455266

ncbi acc num :

NP_859048.1

ncbi gb acc num :

NM_181697.2

ncbi mol weight :

22,110 Da

ncbi pathways :

Androgen Receptor Signaling Pathway (198806); Cellular Responses To Stress Pathway (1270414); Coregulation Of Androgen Receptor Activity Pathway (138085); Detoxification Of Reactive Oxygen Species Pathway (1270420); Gene Expression Pathway (1269649); Generic Transcription Pathway (1269650); Peroxisome Pathway (131226); Peroxisome Pathway (131126); Selenium Pathway (198825); TP53 Regulates Metabolic Genes Pathway (1269655)

ncbi summary :

This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein may play an antioxidant protective role in cells, and may contribute to the antiviral activity of CD8(+) T-cells. This protein may have a proliferative effect and play a role in cancer development or progression. Four transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jan 2011]

uniprot summary :

PRDX1: a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. Involved in redox regulation of the cell. Reduces peroxides with reducing equivalents provided through the thioredoxin system but not from glutaredoxin. May play an important role in eliminating peroxides generated during metabolism. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2). May have a proliferative effect and play a role in cancer development or progression. Protein type: EC 1.11.1.15; Oxidoreductase; Nuclear receptor co-regulator. Chromosomal Location of Human Ortholog: 1p34.1. Cellular Component: cytoplasm; cytosol; extracellular space; melanosome; mitochondrion; myelin sheath; nucleus. Molecular Function: identical protein binding; peroxidase activity; protein binding; thioredoxin peroxidase activity. Biological Process: cell proliferation; erythrocyte homeostasis; hydrogen peroxide catabolic process; natural killer cell mediated cytotoxicity; regulation of NF-kappaB import into nucleus; regulation of stress-activated MAPK cascade; removal of superoxide radicals; response to reactive oxygen species; retinal homeostasis; skeletal development

size1 :

0.1 mg

price1 :

305 USD

more info or order :

MyBioSource product webpage