catalog number :
MBS422207
products full name :
Goat anti-T1R3 Antibody
products short name :
T1R3
products name syn :
Goat Anti-TAS1R3 / T1R3 Antibody; TAS1R3; taste receptor, type 1, member 3; T1R3; TAS1R3 antibody; taste receptor; type 1; member 3 antibody; T1R3 antibody
other names :
taste receptor type 1 member 3; Taste receptor type 1 member 3; taste receptor type 1 member 3; taste 1 receptor member 3; Sweet taste receptor T1R3
products gene name :
TAS1R3
products gene name syn :
T1R3
other gene names :
TAS1R3; TAS1R3; T1R3; T1R3; TR3
uniprot entry name :
TS1R3_HUMAN
reactivity :
Expected from sequence similarity: Human
sequence :
QGQNDGNTGNQGKHE
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA)
app notes :
Peptide ELISA: Antibody detection limit dilution 1: 1000. Western Blot: Not yet tested. At this stage we are dependent on researchers in the field for further characterization of this product. Therefore we cannot recommend an optimal concentration and the product is investigative grade.
other info1 :
Immunogen: Peptide with sequence C-QGQNDGNTGNQGKHE, from the internal region of the protein sequence according to NP_689414.1. Epitope: Internal region
ncbi acc num :
NP_689414.1
ncbi gb acc num :
NM_152228.2
ncbi mol weight :
93,386 Da
ncbi pathways :
Carbohydrate Digestion And Absorption Pathway (170720); Carbohydrate Digestion And Absorption Pathway (170654); Class C/3 (Metabotropic Glutamate/pheromone Receptors) Pathway (1269573); GPCR Ligand Binding Pathway (1269544); Signal Transduction Pathway (1269379); Signaling By GPCR Pathway (1269543); Taste Transduction Pathway (83088); Taste Transduction Pathway (499)
ncbi summary :
The protein encoded by this gene is a G-protein coupled receptor involved in taste responses. The encoded protein can form a heterodimeric receptor with TAS1R1 to elicit the umami taste response, or it can bind with TAS1R2 to form a receptor for the sweet taste response. [provided by RefSeq, Nov 2015]
uniprot summary :
TAS1R3: Putative taste receptor. TAS1R1/TAS1R3 responds to the umami taste stimulus (the taste of monosodium glutamate). TAS1R2/TAS1R3 recognizes diverse natural and synthetic sweeteners. TAS1R3 is essential for the recognition and response to the disaccharide trehalose. Sequence differences within and between species can significantly influence the selectivity and specificity of taste responses. Belongs to the G-protein coupled receptor 3 family. TAS1R subfamily. Protein type: Membrane protein, integral; GPCR, family 3; Membrane protein, multi-pass; Receptor, GPCR. Chromosomal Location of Human Ortholog: 1p36.33. Cellular Component: integral to membrane; plasma membrane. Molecular Function: protein heterodimerization activity; sweet taste receptor activity; taste receptor activity. Biological Process: detection of chemical stimulus involved in sensory perception of sweet taste; G-protein coupled receptor protein signaling pathway; sensory perception of sweet taste; sensory perception of umami taste