catalog number :
MBS422198
products full name :
Goat anti-ABCC1 Antibody
products short name :
ABCC1
products name syn :
ABCC1; ATP-binding cassette; sub-family C (CFTR/MRP); member 1; ABC29; ABCC; DKFZp686N04233; DKFZp781G125; GS-X; MRP; MRP1; ATP-binding cassette; sub-family C; member 1; LTC4 transporter; leukotriene C(4) transporter; multidrug resistance protein; multiple drug resistance protein 1; multiple drug resistance-associated protein; ATP-binding cassette, sub-family C (CFTR/MRP), member 1; ABC29; ABCC; DKFZp686N04233; DKFZp781G125; GS-X; MRP; MRP1; ATP-binding cassette, sub-family C, member 1; LTC4 transporter; leukotriene C(4) transporter; multidrug resistance protein; multiple drug resistance protein 1; multiple drug resistance-associated protein
other names :
multidrug resistance-associated protein 1; Multidrug resistance-associated protein 1; multidrug resistance-associated protein 1; LTC4 transporter; leukotriene C(4) transporter; ATP-binding cassette transporter variant ABCC1delta-ex13; ATP-binding cassette transporter variant ABCC1delta-ex25; ATP-binding cassette transporter variant ABCC1delta-ex13 ATP-binding cassette transporter variant ABCC1delta-ex25 ATP-binding cassette, sub-family C (CFTR/MRP), member 1; ATP-binding cassette sub-family C member 1; Leukotriene C(4) transporter; LTC4 transporter
products gene name :
ABCC1
other gene names :
ABCC1; ABCC1; MRP; ABCC; GS-X; MRP1; ABC29; MRP; MRP1; LTC4 transporter
uniprot entry name :
MRP1_HUMAN
reactivity :
Human, Mouse, Rat, Dog, Cow
sequence :
HQSDLKVDENQKAYY
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Western Blot: Approx 150kDa band observed in lysates of cell line A549 (calculated MW of 159kDa according to NP_063954.2). Recommended concentration:0.05-0.2ug/ml. Peptide ELISA: antibody detection limit dilution 1:128000.
other info1 :
Epitope: Internal Region. Immunogen: Peptide with sequence C-HQSDLKVDENQKAYY, from the internal region of the protein sequence according to NP_004987.2; NP_063915.2; NP_063953.2; NP_063954.2; NP_063955.2. Corresponding Immunizing Peptide: Catalog #MBS426249
other info2 :
Important Note: This antibody is expected to recognize all reported isoforms (NP_004987.2; NP_063915.2; NP_063953.2; NP_063954.2; NP_063955.2).
ncbi acc num :
NP_004987.2
ncbi gb acc num :
NM_004996.3
ncbi mol weight :
172,640 Da
ncbi pathways :
ABC Transporters Pathway 83035!!ABC Transporters Pathway 436!!ABC-family Proteins Mediated Transport Pathway 106573!!Arachidonic Acid Metabolism Pathway 685553!!Cobalamin (Cbl, Vitamin B12) Transport And Metabolism Pathway 833804!!Defective AMN Causes Hereditary Megaloblastic Anemia 1 Pathway 906000!!Defective BTD Causes Biotidinase Deficiency Pathway 906015!!Defective CD320 Causes Methylmalonic Aciduria Pathway 906012!!Defective CUBN Causes Hereditary Megaloblastic Anemia 1 Pathway 906001!!Defective GIF Causes Intrinsic Factor Deficiency Pathway 906004
ncbi summary :
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts. Alternatively spliced variants of this gene have been described but their full-length nature is unknown. [provided by RefSeq, Apr 2012]