catalog number :
MBS422177
products full name :
Goat anti-ABCB8 Antibody
products short name :
ABCB8
products name syn :
ABCB8; ATP-binding cassette; sub-family B (MDR/TAP); member 8; EST328128; M-ABC1; MABC1; ATP-binding cassette; sub-family B; member 8; mitochondrial ABC protein; ATP-binding cassette, sub-family B (MDR/TAP), member 8; EST328128; M-ABC1; MABC1; ATP-binding cassette, sub-family B, member 8; mitochondrial ABC protein
other names :
ATP-binding cassette sub-family B member 8, mitochondrial isoform b; ATP-binding cassette sub-family B member 8, mitochondrial; ATP-binding cassette sub-family B member 8, mitochondrial; mitochondrial ABC protein; mitochondrial ATP-binding cassette 1; ATP-binding cassette, sub-family B (MDR/TAP), member 8; Mitochondrial ATP-binding cassette 1; M-ABC1
products gene name :
ABCB8
other gene names :
ABCB8; ABCB8; MABC1; M-ABC1; EST328128; MABC1; M-ABC1
uniprot entry name :
ABCB8_HUMAN
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA)
app notes :
Western Blot: Preliminary experiments gave an approx 22kDa band in lysates of cell lines HeLa and Jurkat after 0.5ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 78.1kDa according to NP_009119.2. The 22kDa band was successfully blocked by incubation with the immunizing peptide. Peptide ELISA: antibody detection limit dilution 1:128000.
other info1 :
Epitope: C Terminus. Immunogen: Peptide with sequence C-KKPEGPRSHQHK, from the C Terminus of the protein sequence according to NP_009119.2.
other info2 :
Corresponding Immunizing Peptide: Catalog #MBS426536
ncbi acc num :
NP_009119.2
ncbi gb acc num :
NM_007188.4
ncbi mol weight :
59,383 Da
ncbi pathways :
ABC Transporters Pathway 83035!!ABC Transporters Pathway 436!!ABC-family Proteins Mediated Transport Pathway 106573!!Mitochondrial ABC Transporters Pathway 477113!!Transmembrane Transport Of Small Molecules Pathway 106572
ncbi summary :
This nuclear gene encodes a multi-pass membrane protein that is targeted to the mitochondrial inner membrane. The encoded protein is an ATP-dependent transporter that may mediate the passage of organic and inorganic molecules out of the mitochondria. Loss of function of the related gene in mouse results in a disruption of iron homeostasis between the mitochondria and cytosol. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]