antibody

Goat anti-APOB Antibody

MBS422164

0.1 mg

290 USD

polyclonal

goat

nonconjugated

western blot, enzyme immunoassay

Antibody

Goat anti-APOB Antibody

APOB

APOB; apolipoprotein B (including Ag(x) antigen); FLDB; apoB-100; apoB-48; apolipoprotein B; apolipoprotein B48; apolipoprotein B (including Ag(x) antigen); FLDB; apoB-100; apoB-48; apolipoprotein B; apolipoprotein B48

apolipoprotein B-100; Apolipoprotein B-100; apolipoprotein B-100; apoB-48; apoB-100; apo B-100; mutant Apo B 100; apolipoprotein B48; apolipoprotein B (including Ag(x) antigen); apolipoprotein B

APOB

APOB; APOB; FLDB; LDLCQ4; Apo B-100; Apo B-48

APOB_HUMAN

Polyclonal

Goat

Human

4563

TDLHLRYQKDKK

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

100ug specific antibody in 200ul

Aliquot and store at -20 degree C. Minimize freezing and thawing.

Peptide ELISA (EIA), Western Blot (WB)

Western Blot: Bands corresponding to the expected size of ApoB100 were detected in Human serum samples from five different individuals. Recommended concentration: 0.3-1ug/ml. Peptide ELISA: antibody detection limit dilution 1:32000.

Epitope: Internal Region. Immunogen: Peptide with sequence C-TDLHLRYQKDKK, from the internal region of the protein sequence according to NP_000375.2.

Corresponding Immunizing Peptide: Catalog #MBS425592

105990532

NP_000375.2

NM_000384.2

515,605 Da

Binding And Uptake Of Ligands By Scavenger Receptors Pathway 771599!!Cell Surface Interactions At The Vascular Wall Pathway 106062!!Chylomicron-mediated Lipid Transport Pathway 106157!!Disease Pathway 530764!!Diseases Associated With Visual Transduction Pathway 771581!!FOXA1 Transcription Factor Network Pathway 137979!!Fat Digestion And Absorption Pathway 194385!!Fat Digestion And Absorption Pathway 194324!!Hemostasis Pathway 106028!!LDL-mediated Lipid Transport Pathway 106159

This gene product is the main apolipoprotein of chylomicrons and low density lipoproteins. It occurs in plasma as two main isoforms, apoB-48 and apoB-100: the former is synthesized exclusively in the gut and the latter in the liver. The intestinal and the hepatic forms of apoB are encoded by a single gene from a single, very long mRNA. The two isoforms share a common N-terminal sequence. The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA- UAA), resulting in the creation of a stop codon, and early translation termination. Mutations in this gene or its regulatory region cause hypobetalipoproteinemia, normotriglyceridemic hypobetalipoproteinemia, and hypercholesterolemia due to ligand-defective apoB, diseases affecting plasma cholesterol and apoB levels. [provided by RefSeq, Jul 2008]

0.1 mg

290 USD