catalog number :
MBS422157
products full name :
Goat anti-TRPC4 Antibody
products short name :
TRPC4
products name syn :
TRPC4; transient receptor potential cation channel; subfamily C; member 4; HTRP4; MGC119570; MGC119571; MGC119572; MGC119573; TRP4; transient receptor potential 4; TRPC4; transient receptor potential cation channel, subfamily C, member 4; HTRP4; MGC119570; MGC119571; MGC119572; MGC119573; TRP4; transient receptor potential 4
other names :
short transient receptor potential channel 4 isoform alpha; Short transient receptor potential channel 4; short transient receptor potential channel 4; trp-related protein 4; transient receptor potential cation channel, subfamily C, member 4; Trp-related protein 4; hTrp-4; hTrp4
products gene name :
TRPC4
other gene names :
TRPC4; TRPC4; TRP4; HTRP4; HTRP-4; TrpC4; hTrp-4; hTrp4
uniprot entry name :
TRPC4_HUMAN
reactivity :
Human, Mouse, Rat, Dog, Pig, Cow
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Western Blot: Approx. 110kDa band observed in Rat Brain lysates (calculated MW of 112kDa according to Human NP_057263.1 and to Rat NP_536321.1). Recommended concentration: 0.3-1ug/ml. Peptide ELISA: antibody detection limit dilution 1:32000.
other info1 :
Epitope: Internal Region (Near C Terminus). Immunogen: Peptide with sequence C-KHAKEEDSSIDYD, from the internal region (near C Terminus) of the protein sequence according to NP_057263.1; NP_003297.1; NP_001129427.1; NP_001129429.1; NP_001129428.1; NP_001129430.1. Corresponding Immunizing Peptide: Catalog #MBS426556
other info2 :
Important Note: This antibody is expected to recognise all six reported isoforms (NP_057263.1; NP_003297.1; NP_001129427.1; NP_001129429.1; NP_001129428.1; NP_001129430.1).
ncbi acc num :
NP_057263.1
ncbi gb acc num :
NM_016179.2
ncbi mol weight :
36,759 Da
ncbi pathways :
Axon Guidance Pathway 105688!!Developmental Biology Pathway 477129!!Ion Channel Transport Pathway 187193!!Netrin-1 Signaling Pathway 160999!!Role Of Second Messengers In Netrin-1 Signaling Pathway 161002!!Stimuli-sensing Channels Pathway 771568!!TRP Channels Pathway 906028!!Transmembrane Transport Of Small Molecules Pathway 106572
ncbi summary :
This gene encodes a member of the canonical subfamily of transient receptor potential cation channels. The encoded protein forms a non-selective calcium-permeable cation channel that is activated by Gq-coupled receptors and tyrosine kinases, and plays a role in multiple processes including endothelial permeability, vasodilation, neurotransmitter release and cell proliferation. Single nucleotide polymorphisms in this gene may be associated with generalized epilepsy with photosensitivity. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2011]