product summary
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company name :
MyBioSource
product type :
antibody
product name :
Goat anti-mKIAA0319 (mouse) Antibody
catalog :
MBS422150
quantity :
0.1 mg
price :
305 USD
clonality :
polyclonal
host :
goat
conjugate :
nonconjugated
reactivity :
mouse, rat
application :
western blot, enzyme immunoassay
more info or order :
image
image 1 :
(0.5ug/ml) staining of Mouse Brain lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
product information
catalog number :
MBS422150
products type :
Antibody
products full name :
Goat anti-mKIAA0319 (mouse) Antibody
products short name :
[mKIAA0319]
products name syn :
[mKIAA0319; similar to KIAA0319 gene product; 4930451E12Rik; KIAA0319; mKIAA0319 antibody; similar to KIAA0319 gene product antibody; 4930451E12Rik antibody; KIAA0319 antibody; mKIAA0319 (mouse)]
other names :
[dyslexia-associated protein KIAA0319 homolog; Dyslexia-associated protein KIAA0319 homolog; dyslexia-associated protein KIAA0319 homolog; RIKEN cDNA D130043K22 gene]
products gene name :
[D130043K22Rik]
products gene name syn :
[mKIAA0319]
other gene names :
[D130043K22Rik; Kiaa0319; Kiaa0319; 4930451E12Rik]
uniprot entry name :
K0319_MOUSE
clonality :
Polyclonal
host :
Goat
reactivity :
Tested: Mouse; Expected from sequence similarity: Mouse, Rat
sequence length :
1081
sequence :
QGKIKQENKPTLH
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Peptide ELISA: Antibody detection limit dilution 1: 128000.
image1 heading :
Western Blot (WB)
other info1 :
Immunogen: Peptide with sequence C-QGKIKQENKPTLH, from the internal region of the protein sequence according to NP_001074520.1. Epitope: Internal region
other info2 :
Note: The variants XP_341528.2 and XP_001070349.1 represent identical protein. This antibody is expected to cross-react with mouse KIAA0319 isoform 1 (NP_001074520.1), isoform 2 (XP_994023.1) and isoform 4 (XP_913491.1).
ncbi gi num :
124486676
ncbi acc num :
NP_001074520.1
ncbi gb acc num :
NM_001081051.2
ncbi mol weight :
117,988 Da
ncbi summary :
This gene encodes a transmembrane protein that contains a large extracellular domain with multiple polycystic kidney disease (PKD) domains. The encoded protein may play a role in the development of the cerebral cortex by regulating neuronal migration and cell adhesion. Single nucleotide polymorphisms in a similar gene in human are associated with dyslexia. Alternatively spliced transcript variants have been identifed. [provided by RefSeq, May 2015]
uniprot summary :
KIAA0319: Involved in neuronal migration during development of the cerebral neocortex. May function in a cell autonomous and a non- cell autonomous manner and play a role in appropriate adhesion between migrating neurons and radial glial fibers. May also regulate growth and differentiation of dendrites. Defects in KIAA0319 may be a cause of susceptibility to dyslexia type 2 (DYX2); also known as specific reading disability type 2. Dyslexia is a relatively common, complex cognitive disorder that affects 5% to 10% of school-aged children. The disorder is characterized by an impairment of reading performance despite adequate motivational, educational and intellectual opportunities and in the absence of sensory or neurological disability. A lower expression is associated with the risk haplotype. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, integral. Cellular Component: early endosome; endosome; integral to membrane; membrane; plasma membrane. Biological Process: multicellular organismal development; nervous system development; neuron migration
size1 :
0.1 mg
price1 :
305 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
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