product summary
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company name :
MyBioSource
product type :
antibody
product name :
Goat anti-NFATC2 / NFAT1 Antibody
catalog :
MBS422143
quantity :
0.1 mg
price :
290 USD
clonality :
polyclonal
host :
goat
conjugate :
nonconjugated
reactivity :
human, mouse, rat, dog, cow
application :
western blot, immunohistochemistry, enzyme immunoassay
more info or order :
product information
catalog number :
MBS422143
products type :
Antibody
products full name :
Goat anti-NFATC2 / NFAT1 Antibody
products short name :
NFATC2/NFAT1
products name syn :
NFATC2; nuclear factor of activated T-cells; cytoplasmic; calcineurin-dependent 2; KIAA0611; NFAT1; NFATP; NFAT pre-existing subunit; NFAT transcription complex; preexisting component; OTTHUMP00000031291; T cell transcription factor NFAT1; nuclear factor of activated T-cells; cytoplasmic 2; nuclear factor of activated T-cells; preexisting component; preexisting nuclear factor of activated T-cells 2; NFATC2; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2; KIAA0611; NFAT1; NFATP; NFAT pre-existing subunit; NFAT transcription complex, preexisting component; OTTHUMP00000031291; T cell transcription factor NFAT1; nuclear factor of activated T-cells, cytoplasmic 2; nuclear factor of activated T-cells, preexisting component; preexisting nuclear factor of activated T-cells 2
other names :
nuclear factor of activated T-cells, cytoplasmic 2 isoform B; Nuclear factor of activated T-cells, cytoplasmic 2; nuclear factor of activated T-cells, cytoplasmic 2; NF-ATc2; NFAT pre-existing subunit; T cell transcription factor NFAT1; T-cell transcription factor NFAT1; NFAT transcription complex, preexisting component; preexisting nuclear factor of activated T-cells 2; nuclear factor of activated T-cells, preexisting component; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2; NFAT pre-existing subunit; NF-ATp; T-cell transcription factor NFAT1
products gene name :
NFATC2
other gene names :
NFATC2; NFATC2; NFAT1; NFATP; NFAT1; NFATP; NF-ATc2; NFATc2; NF-ATp
uniprot entry name :
NFAC2_HUMAN
clonality :
Polyclonal
host :
Goat
reactivity :
Human, Mouse, Rat, Dog, Cow
sequence length :
921
sequence :
QQFRTGLSSPDARYQ
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
app notes :
Immunohistochemistry: In paraffin embedded Human Spleen shows nuclear membrane and weaker cytoplasm staining in select splenocytes. Recommended concentration, 3-6ug/ml. Western Blot: Approx 110kDa band observed in Human lysates of cell line MOLT4 (calculated MW of 100kDa according to NP_775114.1). Recommended concentration: 0.3-1ug/ml. Peptide ELISA: antibody detection limit dilution 1:64000.
other info1 :
Epitope: Internal Region. Immunogen: Peptide with sequence C-QQFRTGLSSPDARYQ, from the internal region of the protein sequence according to NP_036472.2; NP_775114.1; NP_001129493.1. Corresponding Immunizing Peptide: Catalog #MBS426647
other info2 :
Important Note: This antibody is expected to recognize all three reported isoforms (NP_036472.2; NP_775114.1; NP_001129493.1).
ncbi gi num :
27886539
ncbi acc num :
NP_036472.2
ncbi gb acc num :
NM_012340.4
ncbi mol weight :
76,700 Da
ncbi pathways :
Axon Guidance Pathway 83065!!Axon Guidance Pathway 476!!B Cell Receptor Signaling Pathway 198909!!B Cell Receptor Signaling Pathway 83081!!B Cell Receptor Signaling Pathway 492!!Calcineurin-regulated NFAT-dependent Transcription In Lymphocytes Pathway 137993!!Calcium Signaling In The CD4+ TCR Pathway 137941!!Downstream Signaling In Naive CD8+ T Cells Pathway 138018!!FCERI Mediated Ca+2 Mobilization Pathway 833827!!Fc Epsilon Receptor (FCERI) Signaling Pathway 833825
ncbi summary :
This gene is a member of the nuclear factor of activated T cells (NFAT) family. The product of this gene is a DNA-binding protein with a REL-homology region (RHR) and an NFAT-homology region (NHR). This protein is present in the cytosol and only translocates to the nucleus upon T cell receptor (TCR) stimulation, where it becomes a member of the nuclear factors of activated T cells transcription complex. This complex plays a central role in inducing gene transcription during the immune response. Alternate transcriptional splice variants encoding different isoforms have been characterized. [provided by RefSeq, Apr 2012]
size :
0.1 mg
price :
290 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
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