catalog number :
MBS422139
products full name :
Goat anti-ABCA12 Antibody
products short name :
ABCA12
products name syn :
ABCA12; ATP-binding cassette; sub-family A (ABC1); member 12; DKFZp434G232; FLJ41584; ICR2B; LI2; ATP-binding cassette; sub-family A; member 12; ATP-binding cassette, sub-family A (ABC1), member 12; DKFZp434G232; FLJ41584; ICR2B; LI2; ATP-binding cassette, sub-family A, member 12
other names :
ATP-binding cassette sub-family A member 12 isoform a; ATP-binding cassette sub-family A member 12; ATP-binding cassette sub-family A member 12; ATP-binding cassette transporter 12; ATP-binding cassette, sub-family A (ABC1), member 12; ATP-binding cassette transporter 12; ATP-binding cassette 12
products gene name :
ABCA12
other gene names :
ABCA12; ABCA12; LI2; ICR2B; ARCI4A; ARCI4B; ABC12; ATP-binding cassette 12
uniprot entry name :
ABCAC_HUMAN
sequence :
KDQKSYETADTSSQ
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA)
app notes :
Western Blot: Preliminary experiments gave an approx 35kDa band in Human Placenta, Skin and Testis lysates after 1ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 193kDa according to NP_775099.2 and of 257kDa according to NP_056472.2. The 35kDa band was successfully blocked by incubation with the immunizing peptide. Peptide ELISA: antibody detection limit dilution 1:1000.
other info1 :
Epitope: Internal Region (Near C Terminus). Immunogen: Peptide with sequence C-KDQKSYETADTSSQ, from the internal regon (near C terminus) of the protein sequence according to NP_775099.2; NP_056472.2. Corresponding Immunizing Peptide: Catalog #MBS426242
other info2 :
Important Note: This antibody is expected to recognize both reported isoforms (NP_775099.2; NP_056472.2).
ncbi acc num :
NP_775099.2
ncbi gb acc num :
NM_173076.2
ncbi mol weight :
256,960 Da
ncbi pathways :
ABC Transporters Pathway 83035!!ABC Transporters Pathway 436!!ABC-family Proteins Mediated Transport Pathway 106573!!ABCA Transporters In Lipid Homeostasis Pathway 477112!!Transmembrane Transport Of Small Molecules Pathway 106572
ncbi summary :
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This encoded protein is a member of the ABC1 subfamily, which is the only major ABC subfamily found exclusively in multicellular eukaryotes. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008]