Goat anti-CXCL1 Antibody | MyBioSource MBS422132 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Goat anti-CXCL1 Antibody

catalog :

MBS422132

quantity :

0.1 mg

price :

225 USD

clonality :

polyclonal

host :

goat

conjugate :

nonconjugated

reactivity :

human

application :

ELISA, enzyme immunoassay

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS422132

products type :

Antibody

products full name :

Goat anti-CXCL1 Antibody

products short name :

CXCL1

products name syn :

CXCL1; chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha); FSP; GRO1; GROa; MGSA; MGSA-a; NAP-3; SCYB1; GRO1 oncogene (melanoma growth stimulating activity, alpha); GRO1 oncogene (melanoma growth-stimulating activity); MGSA alp; CXCL1 antibody; chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity; alpha) antibody; FSP antibody; GRO1 antibody; GROa antibody; MGSA antibody; MGSA-a antibody; NAP-3 antibody; SCYB1 antibody; GRO1 oncogene (melanoma growth stimulating activity; alpha) antibody; GRO1 oncogene (melanoma growth-stimulating activity) antibody; MGSA alpha antibody; chemokine (C-X-C motif) ligand 1 antibody; fibroblast secretory protein antibody; melanoma growth stimulatory activity alpha antibody

other names :

growth-regulated alpha protein; Growth-regulated alpha protein; growth-regulated alpha protein; C-X-C motif chemokine ligand 1; C-X-C motif chemokine 1; GRO-alpha(1-73); Melanoma growth stimulatory activity; MGSA

products gene name :

CXCL1

other gene names :

CXCL1; CXCL1; FSP; GRO1; GROa; MGSA; NAP-3; SCYB1; MGSA-a; GRO; GRO1; GROA; MGSA; SCYB1; MGSA; NAP-3

uniprot entry name :

GROA_HUMAN

clonality :

Polyclonal

host :

Goat

reactivity :

Expected from sequence similarity: Human

sequence length :

107

sequence :

EKMLNSDKSN

purity :

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

form :

Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

concentration :

100ug specific antibody in 200ul

storage stability :

Aliquot and store at -20 degree C. Minimize freezing and thawing.

tested application :

Peptide ELISA (EIA)

app notes :

Peptide ELISA: Antibody detection limit dilution 1: 2000. Western Blot: Not yet tested - our routinely used western blotting protocol does not allow detection of proteins as small as the calculated size of 11.3kDa according to NP_001502.1. Therefore we cannot recommend an optimal concentration and the antibody is an aspiring product.

other info1 :

Immunogen: Peptide with sequence C-EKMLNSDKSN, from the C Terminus of the protein sequence according to NP_001502.1. Epitope: C Terminus

ncbi gi num :

4504153

ncbi acc num :

NP_001502.1

ncbi gb acc num :

NM_001511.3

ncbi mol weight :

11,301 Da

ncbi pathways :

Amoebiasis Pathway (167324); Amoebiasis Pathway (167191); Chemokine Receptors Bind Chemokines Pathway (1269547); Chemokine Signaling Pathway (99051); Chemokine Signaling Pathway (96864); Class A/1 (Rhodopsin-like Receptors) Pathway (1269545); Cytokine-cytokine Receptor Interaction Pathway (83051); Cytokine-cytokine Receptor Interaction Pathway (460); Cytokines And Inflammatory Response Pathway (198794); Epithelial Cell Signaling In Helicobacter Pylori Infection Pathway (83102)

ncbi summary :

This antimicrobial gene encodes a member of the CXC subfamily of chemokines. The encoded protein is a secreted growth factor that signals through the G-protein coupled receptor, CXC receptor 2. This protein plays a role in inflammation and as a chemoattractant for neutrophils. Aberrant expression of this protein is associated with the growth and progression of certain tumors. A naturally occurring processed form of this protein has increased chemotactic activity. Alternate splicing results in coding and non-coding variants of this gene. A pseudogene of this gene is found on chromosome 4. [provided by RefSeq, Sep 2014]

uniprot summary :

CXCL1: Has chemotactic activity for neutrophils. May play a role in inflammation and exerts its effects on endothelial cells in an autocrine fashion. In vitro, the processed forms GRO- alpha(4-73), GRO-alpha(5-73) and GRO-alpha(6-73) show a 30-fold higher chemotactic activity. Belongs to the intercrine alpha (chemokine CxC) family. Protein type: Secreted; Secreted, signal peptide; Motility/polarity/chemotaxis. Chromosomal Location of Human Ortholog: 4q21. Cellular Component: extracellular region; extracellular space; intracellular. Molecular Function: chemokine activity; CXCR chemokine receptor binding; enzyme activator activity; growth factor activity; receptor binding. Biological Process: actin cytoskeleton organization and biogenesis; cell proliferation; chemotaxis; G-protein coupled receptor protein signaling pathway; immune response; inflammatory response; negative regulation of cell proliferation; nervous system development; positive regulation of catalytic activity; response to lipopolysaccharide; signal transduction

size1 :

0.1 mg

price1 :

225 USD

more info or order :

MyBioSource product webpage