catalog number :
MBS422088
products full name :
Goat anti-ALOX15 Antibody
products short name :
ALOX15
products name syn :
ALOX15; arachidonate 15-lipoxygenase; 15-LOX-1; 15-LOX2; ALOX15 antibody; arachidonate 15-lipoxygenase antibody; 15-LOX-1 antibody; 15-LOX2 antibody
other names :
arachidonate 15-lipoxygenase; Arachidonate 15-lipoxygenase; arachidonate 15-lipoxygenase; arachidonate 15-lipoxygenase; 12/15-lipoxygenase; Arachidonate 12-lipoxygenase, leukocyte-type (EC:1.13.11.31
products gene name :
ALOX15
other gene names :
ALOX15; ALOX15; 12-LOX; 15LOX-1; 15-LOX-1; LOG15; 12-LOX
uniprot entry name :
LOX15_HUMAN
reactivity :
Tested: Human; Expected from sequence similarity: Human
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Peptide ELISA: Antibody detection limit dilution 1: 32000. Western Blot: Approx.80kDa band observed in nuclear lysates of cell line HeLa (calculated MW of 74.8kDa according to NP_001131.3). Recommended concentration: 0.2-0.5ug/ml.
other info1 :
Immunogen: Peptide with sequence C-HYKTDVAVKDDPE, from the internal region of the protein sequence according to NP_001131.3. Epitope: Internal region
ncbi acc num :
NP_001131.3
ncbi gb acc num :
NM_001140.3
ncbi mol weight :
70,108 Da
ncbi pathways :
Arachidonic Acid Metabolism Pathway (82991); Arachidonic Acid Metabolism Pathway (1270087); Arachidonic Acid Metabolism Pathway (366); Eicosanoid Synthesis Pathway (198888); IL4-mediated Signaling Events Pathway (137933); Linoleic Acid Metabolism Pathway (82992); Linoleic Acid Metabolism Pathway (367); Metabolic Pathways (132956); Metabolism Pathway (1269956); Metabolism Of Lipids And Lipoproteins Pathway (1270001)
uniprot summary :
ALOX15: Converts arachidonic acid to 15S- hydroperoxyeicosatetraenoic acid. Also acts on C-12 of arachidonate as well as on linoleic acid. Belongs to the lipoxygenase family. Protein type: Lipid Metabolism - arachidonic acid; Oxidoreductase; EC 1.13.11.33; Motility/polarity/chemotaxis; Lipid Metabolism - linoleic acid; EC 1.13.11.31. Chromosomal Location of Human Ortholog: 17p13.3. Cellular Component: cytosol; extrinsic to internal side of plasma membrane; lipid particle; membrane; plasma membrane. Molecular Function: arachidonate 12-lipoxygenase activity; arachidonate 15-lipoxygenase activity; hepoxilin A3 synthase activity; hepoxilin-epoxide hydrolase activity; iron ion binding; phosphatidylinositol-4,5-bisphosphate binding; protein binding. Biological Process: apoptotic cell clearance; arachidonic acid metabolic process; bone mineralization; hepoxilin biosynthetic process; inflammatory response; leukotriene metabolic process; lipoxygenase pathway; negative regulation of adaptive immune response; ossification; phosphatidylethanolamine biosynthetic process; positive regulation of actin filament polymerization; positive regulation of heterotypic cell-cell adhesion; wound healing