catalog number :
MBS422080
products full name :
Goat anti-Annexin I Antibody
products short name :
Annexin I
products name syn :
annexin I; ANXA1; annexin A1; ANX1; LPC1; annexin I (lipocortin I); lipocortin I; annexin I; annexin A1; ANX1; LPC1; annexin I (lipocortin I); lipocortin I
other names :
annexin A1; Annexin A1; annexin A1; annexin-1; calpactin-2; calpactin II; chromobindin-9; annexin I (lipocortin I); phospholipase A2 inhibitory protein; annexin A1; Annexin I; Annexin-1; Calpactin II; Calpactin-2; Chromobindin-9; Lipocortin I; Phospholipase A2 inhibitory protein; p35
products gene name :
ANXA1
other gene names :
ANXA1; ANXA1; ANX1; LPC1; ANX1; LPC1
uniprot entry name :
ANXA1_HUMAN
reactivity :
Human, Mouse, Rat, Dog, Cow, Pig
sequence :
CQAILDETKGDYEK
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Western Blot: Approx 35kDa band observed in Human lysates of cell lines A431 and K562 (calculated MW of 38.7kDa according to NP_000691.1). The observed molecular weight corresponds to earlier findings in literature with different antibodies (Paweletz et al, Cancer Res. 2000 Nov15;60(22):6293-7. PMID: 11103786). A 37kDa band is observed in lysates of Rat Spleen. Recommended concentration: 1-3 ug/ml. Peptide ELISA: antibody detection limit dilution 1:4000.
other info1 :
Epitope: C Terminus. Immunogen: Peptide with sequence CQAILDETKGDYEK, from the C Terminus of the protein sequence according to NP_000691.1.
other info2 :
Corresponding Immunizing Peptide: Catalog #MBS426331
ncbi acc num :
NP_000691.1
ncbi gb acc num :
NM_000700.2
ncbi mol weight :
38,714 Da
ncbi pathways :
Class A/1 (Rhodopsin-like Receptors) Pathway 106357!!Formyl Peptide Receptors Bind Formyl Peptides And Many Other Ligands Pathway 161021!!G Alpha (i) Signalling Events Pathway 119550!!G Alpha (q) Signalling Events Pathway 106043!!GPCR Downstream Signaling Pathway 119548!!GPCR Ligand Binding Pathway 161020!!Gastrin-CREB Signalling Pathway Via PKC And MAPK 645295!!Integrated Breast Cancer Pathway 219801!!Integrated Pancreatic Cancer Pathway 711360!!Peptide Ligand-binding Receptors Pathway 106358
ncbi summary :
This gene encodes a membrane-localized protein that binds phospholipids. This protein inhibits phospholipase A2 and has anti-inflammatory activity. Loss of function or expression of this gene has been detected in multiple tumors. [provided by RefSeq, Dec 2014]