catalog number :
MBS422078
products full name :
Goat anti-Arylsulfatase H Antibody
products short name :
Arylsulfatase H
products name syn :
ARSH; arylsulfatase family; member H; sulfatase; arylsulfatase H; arylsulfatase family, member H; sulfatase; arylsulfatase H
other names :
arylsulfatase H; Arylsulfatase H; arylsulfatase H; ASH; arylsulfatase family, member H
products gene name :
ARSH
other gene names :
ARSH; ARSH; sulfatase; ASH
uniprot entry name :
ARSH_HUMAN
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA)
app notes :
Western Blot: Preliminary experiments gave an approx 45kDa band in Human Kidney lysates after 1ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 63.5kDa according to NP_001011719.1. The 45kDa band was successfully blocked by incubation with the immunizing peptide. Peptide ELISA: antibody detection limit dilution 1:4000.
other info1 :
Epitope: Internal Region. Immunogen: Peptide with sequence LSDCQASKTPEL, from the internal region of the protein sequence according to NP_001011719.1.
other info2 :
Corresponding Immunizing Peptide: Catalog #MBS426723
ncbi acc num :
NP_001011719.1
ncbi gb acc num :
NM_001011719.1
ncbi mol weight :
63,525 Da
ncbi pathways :
Glycosphingolipid Metabolism Pathway 530751!!Metabolism Pathway 477135!!Metabolism Of Lipids And Lipoproteins Pathway 160976!!Metabolism Of Proteins Pathway 106230!!PTM: Gamma Carboxylation, Hypusine Formation And Arylsulfatase Activation Pathway 106231!!Post-translational Protein Modification Pathway 161012!!Sphingolipid Metabolism Pathway 119543!!The Activation Of Arylsulfatases Pathway 645291
ncbi summary :
Sulfatases, such as ARSH, hydrolyze sulfate esters from sulfated steroids, carbohydrates, proteoglycans, and glycolipids. They are involved in hormone biosynthesis, modulation of cell signaling, and degradation of macromolecules (Sardiello et al., 2005 [PubMed 16174644]).[supplied by OMIM, Mar 2008]