antibody

Goat anti-ABCA8 Antibody

MBS422044

0.1 mg

225 USD

polyclonal

goat

nonconjugated

ELISA, enzyme immunoassay

Antibody

Goat anti-ABCA8 Antibody

ABCA8

ABCA8; ATP-binding cassette; sub-family A (ABC1); member 8; KIAA0822; MGC163152; ATP-binding cassette; sub-family A member 8; ATP-binding cassette, sub-family A (ABC1), member 8; KIAA0822; MGC163152; ATP-binding cassette, sub-family A member 8

ATP-binding cassette sub-family A member 8 isoform 2; ATP-binding cassette sub-family A member 8; ATP-binding cassette sub-family A member 8; ATP-binding cassette, sub-family A (ABC1), member 8

ABCA8

ABCA8; ABCA8; KIAA0822

ABCA8_HUMAN

Polyclonal

Goat

Human

1581

KEQELGDFEEDFD

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

100ug specific antibody in 200ul

Aliquot and store at -20 degree C. Minimize freezing and thawing.

Peptide ELISA (EIA)

Western Blot: Preliminary experiments gave an approx. 50-55kDa band in Human Brain (Cerebellum, Cerebral Cortex, Frontal Cortex), Heart, Skeletal Muscle and Testis lysates after 0.3ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 179kDa according to NP_009099.1. The 50-55kDa band was successfully blocked by incubation with the immunizing peptide. Peptide ELISA: antibody detection limit dilution 1:4000.

Epitope: C Terminus. Immunogen: Peptide with sequence C-KEQELGDFEEDFD, from the C Terminus of the protein sequence according to NP_009099.1. Corresponding Immunizing Peptide: Catalog #MBS425865

Important Note: This antibody is expected to cross-react with the highly similar Human ABCA9, since the immunizing peptide differs from ABCA9 with only one residue (F8).

6005701

NP_009099.1

NM_007168.3

183,677 Da

ABC Transporters Pathway 83035!!ABC Transporters Pathway 436!!ABC-family Proteins Mediated Transport Pathway 106573!!Transmembrane Transport Of Small Molecules Pathway 106572

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. The encoded protein may regulate lipid metabolism and be involved in the formation and maintenance of myelin. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]

0.1 mg

225 USD