catalog number :
MBS422035
products full name :
Goat anti-COX4I2 & COX4I1 Antibody
products short name :
COX4I2 & COX4I1
products name syn :
COX4I2; cytochrome c oxidase subunit IV isoform 2 (lung); COX4; COX4-2; COX4B; COX4L2; COXIV-2; dJ857M17.2; cytochrome c oxidase subunit IV isoform 2; cytochrome c oxidase subunit IV-like 2; COX4I2; cytochrome c oxidase subunit IV isoform 2 (lung); COX4; COX4-2; COX4B; COX4L2; COXIV-2; dJ857M17.2; cytochrome c oxidase subunit IV isoform 2; cytochrome c oxidase subunit IV-like 2
other names :
cytochrome c oxidase subunit 4 isoform 2, mitochondrial; Cytochrome c oxidase subunit 4 isoform 2, mitochondrial; cytochrome c oxidase subunit 4 isoform 2, mitochondrial; COX IV-2; cytochrome c oxidase subunit IV-like 2; cytochrome c oxidase subunit IV isoform 2 (lung); Cytochrome c oxidase subunit IV isoform 2; COX IV-2
products gene name :
COX4I2
other gene names :
COX4I2; COX4I2; COX4; COX4B; COX4-2; COX4L2; COXIV-2; dJ857M17.2; COX4L2; COX IV-2
uniprot entry name :
COX42_HUMAN
reactivity :
Human, Mouse, Rat, Dog
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Western Blot: Approx 17kDa band observed in Human Skeletal Muscle lysates (calculated MW of 19.6kDa according to NP_115998.2). Recommended concentration: 1-3ug/ml. Peptide ELISA: antibody detection limit dilution 1:2000.
other info1 :
Epitope: C Terminus. Immunogen: Peptide with sequence C-RWDYEKKQWKK, from the C Terminus of the protein sequence according to NP_115998.2. Corresponding Immunizing Peptide: Catalog #MBS425747
other info2 :
Important Note: This antibody is expected to recognize COX4I1 (GeneID:1327; MW: 19.6kDa) & COX4I2 (GeneID:84701, MW:19.6kDa).
ncbi acc num :
NP_115998.2
ncbi gb acc num :
NM_032609.2
ncbi mol weight :
20,010 Da
ncbi pathways :
Alzheimer's Disease Pathway 83097!!Alzheimer's Disease Pathway 509!!Cardiac Muscle Contraction Pathway 93344!!Cardiac Muscle Contraction Pathway 93992!!Cytochrome C Oxidase Pathway 413434!!Cytochrome C Oxidase Pathway 468345!!Huntington's Disease Pathway 83100!!Huntington's Disease Pathway 512!!Metabolic Pathways 132956!!Non-alcoholic Fatty Liver Disease (NAFLD) Pathway 862188
ncbi summary :
Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes isoform 2 of subunit IV. Isoform 1 of subunit IV is encoded by a different gene, however, the two genes show a similar structural organization. Subunit IV is the largest nuclear encoded subunit which plays a pivotal role in COX regulation. [provided by RefSeq, Jul 2008]