antibody

Goat anti-ABCD4 Antibody

MBS422017

0.1 mg

290 USD

polyclonal

goat

nonconjugated

human, mouse, rat, dog

western blot, enzyme immunoassay

Antibody

Goat anti-ABCD4 Antibody

ABCD4

ABCD4; ATP-binding cassette; sub-family D (ALD); member 4; ABC41; EST352188; P70R; P79R; PMP69; PXMP1L; ATP-binding cassette; sub-family D; member 4; peroxisomal membrane protein 1-like; ATP-binding cassette, sub-family D (ALD), member 4; ABC41; EST352188; P70R; P79R; PMP69; PXMP1L; ATP-binding cassette, sub-family D, member 4; peroxisomal membrane protein 1-like

ATP-binding cassette sub-family D member 4; ATP-binding cassette sub-family D member 4; ATP-binding cassette sub-family D member 4; PXMP1-L; PMP70-related protein; peroxisomal membrane protein 69; 69 kDa peroxisomal ABC-transporter; ATP-binding cassette, sub-family D (ALD), member 4; PMP70-related protein; P70R; Peroxisomal membrane protein 1-like; PXMP1-L; Peroxisomal membrane protein 69; PMP69

ABCD4

ABCD4; ABCD4; P70R; P79R; ABC41; MAHCJ; PMP69; PXMP1L; EST352188; PXMP1L; P70R; PXMP1-L; PMP69

ABCD4_HUMAN

Polyclonal

Goat

Human, Mouse, Rat, Dog

606

RDDIDNPDQRISQD

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

100ug specific antibody in 200ul

Aliquot and store at -20 degree C. Minimize freezing and thawing.

Peptide ELISA (EIA), Western Blot (WB)

Western Blot: Approx 70kDa band observed in lysates of cell lines Jurkat and MOLT4 (calculated MW of 68.6kDa according to NP_005041.1). Recommended concentration: 0.3-1ug/ml. Peptide ELISA: antibody detection limit dilution 1:8000.

Epitope: Internal Region. Immunogen: Peptide with sequence C-RDDIDNPDQRISQD, from the internal region of the protein sequence according to NP_005041.1. Corresponding Immunizing Peptide: Catalog #MBS426038

Important Note: Reported variants represent identical protein: NP_064719.1 NP_064731.1 NP_064720.1 NP_064730.1

4826958

NP_005041.1

NM_005050.3

68,597 Da

ABC Transporters Pathway 83035!!ABC Transporters Pathway 436!!Peroxisome Pathway 131226!!Peroxisome Pathway 131126

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown. However, it is speculated that it may function as a heterodimer for another peroxisomal ABC transporter and, therefore, may modify the adrenoleukodystrophy phenotype. It may also play a role in the process of peroxisome biogenesis. Alternative splicing results in at least two different transcript variants, one which is protein-coding and one which is probably not protein-coding. [provided by RefSeq, Jul 2008]

0.1 mg

290 USD