Goat anti-Arginase I Antibody | MyBioSource MBS422008 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Goat anti-Arginase I Antibody

catalog :

MBS422008

quantity :

0.1 mg

price :

300 USD

clonality :

polyclonal

host :

goat

conjugate :

nonconjugated

reactivity :

human, mouse, rat, dog, cow

application :

western blot, enzyme immunoassay

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS422008

products type :

Antibody

products full name :

Goat anti-Arginase I Antibody

products short name :

Arginase I

products name syn :

Goat Anti-Arginase, type 1 / ARG1 Antibody; ARG1; arginase, liver; HGNC: 663; A-I; arginase, type I; arginase 1; liver-type arginase; type I arginase; ARG1 antibody; arginase; liver antibody; HGNC: 663 antibody; A-I antibody; arginase; type I antibody; arginase 1 antibody; liver-type arginase antibody; type I arginase antibody; Arginase I; Arginase I

other names :

arginase-1 isoform 2; Arginase-1; arginase-1; arginase 1; Liver-type arginase; Type I arginase

products gene name :

ARG1

other gene names :

ARG1; ARG1

uniprot entry name :

ARGI1_HUMAN

clonality :

Polyclonal

host :

Goat

reactivity :

Tested: Human, Mouse, Rat, Pig; Expected from sequence similarity: Human, Mouse, Rat, Dog, Pig, Cow

sequence length :

322

sequence :

CFGLAREGNHKPID

purity :

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

form :

Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

concentration :

100ug specific antibody in 200ul

storage stability :

Aliquot and store at -20 degree C. Minimize freezing and thawing.

tested application :

Peptide ELISA (EIA), Western Blot (WB)

app notes :

Peptide ELISA: Antibody detection limit dilution 1: 64000. Western Blot: Approx.37kDa band observed in Human, Mouse, Rat and Pig Liver lysates (calculated MW of 34.7kDa according to NP_000036.2). The observed molecular weight corresponds to earlier findings with different antibodies from other commercial sources. Recommended concentration: 0.01-0.03ug/ml.

other info1 :

Immunogen: Peptide with sequence CFGLAREGNHKPID, from the C Terminus of the protein sequence according to NP_000036.2. Epitope: C Terminus

ncbi gi num :

10947139

ncbi acc num :

NP_000036.2

ncbi gb acc num :

NM_000045.3

ncbi mol weight :

25,356 Da

ncbi pathways :

ATF-2 Transcription Factor Network Pathway (138006); Amoebiasis Pathway (167324); Amoebiasis Pathway (167191); Arginine And Proline Metabolism Pathway (82957); Arginine And Proline Metabolism Pathway (323); Arginine Biosynthesis Pathway (82943); Arginine Biosynthesis Pathway (306); Biosynthesis Of Amino Acids Pathway (790012); Biosynthesis Of Amino Acids Pathway (795174); IL4-mediated Signaling Events Pathway (137933)

ncbi summary :

Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform encoded by this gene, is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]

uniprot summary :

ARG1: Homotrimer. By arginine or homoarginine. Belongs to the arginase family. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Amino Acid Metabolism - arginine and proline; EC 3.5.3.1; Hydrolase. Chromosomal Location of Human Ortholog: 6q23. Cellular Component: cell soma; cytoplasm; cytosol; extracellular space; mitochondrial outer membrane; neuron projection; nucleus. Molecular Function: arginase activity; manganese ion binding. Biological Process: aging; arginine catabolic process; arginine catabolic process to ornithine; collagen biosynthetic process; liver development; lung development; mammary gland involution; maternal process involved in pregnancy; positive regulation of endothelial cell proliferation; response to amine stimulus; response to amino acid stimulus; response to axon injury; response to cadmium ion; response to drug; response to herbicide; response to manganese ion; response to methylmercury; response to selenium ion; response to vitamin A; response to vitamin E; response to zinc ion; urea cycle. Disease: Argininemia

size1 :

0.1 mg

price1 :

300 USD

more info or order :

MyBioSource product webpage