antibody

Goat anti-ABCE1 / RNase L Antibody

MBS422004

0.1 mg

225 USD

polyclonal

goat

nonconjugated

human, mouse, rat, dog, cow

ELISA, enzyme immunoassay

Antibody

Goat anti-ABCE1 / RNase L Antibody

ABCE1/RNase L

ABCE1; ATP-binding cassette; sub-family E (OABP); member 1; ABC38; OABP; RLI; RNASEL1; RNASELI; RNS4I; ATP-binding cassette; sub-family E; member 1; RNase L inhibitor; ribonuclease L (2 1; 5 1-oligoisoadenylate synthetase-dependent) inhibitor; Goat Anti-ABCE1/ RNAse L inhibitor; ATP-binding cassette, sub-family E (OABP), member 1; ABC38; OABP; RLI; RNASEL1; RNASELI; RNS4I; ATP-binding cassette, sub-family E, member 1; RNase L inhibitor; ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) inhibitor

ATP-binding cassette sub-family E member 1; ATP-binding cassette sub-family E member 1; ATP-binding cassette sub-family E member 1; huHP68; RNase L inhibitor; ribonuclease 4 inhibitor; 2'-5'-oligoadenylate-binding protein; ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) inhibitor; ATP-binding cassette, sub-family E (OABP), member 1; 2'-5'-oligoadenylate-binding protein; HuHP68; RNase L inhibitor; Ribonuclease 4 inhibitor; RNS4I

ABCE1

ABCE1; ABCE1; RLI; OABP; ABC38; RNS4I; RNASEL1; RNASELI; RLI; RNASEL1; RNASELI; RNS4I; RNS4I

ABCE1_HUMAN

Polyclonal

Goat

Human, Mouse, Rat, Dog, Cow

599

NHDKCKPKKCRQEC

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

100ug specific antibody in 200ul

Aliquot and store at -20 degree C. Minimize freezing and thawing.

Peptide ELISA (EIA)

Western Blot: Preliminary experiments gave an approx. 80kDa band in Human Spleen lysates after 0.2ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 67.3kDa according to NP_002931.2. The ~80kDa band was successfully blocked by incubation with the immunizing peptide. Peptide ELISA: antibody detection limit dilution 1:32000.

Epitope: N Terminus. Immunogen: Peptide with sequence NHDKCKPKKCRQEC, from the N Terminus of the protein sequence according to NP_002931.2; NP_001035809.1. Corresponding Immunizing Peptide: Catalog #MBS425125

Important Note: Reported variants represent identical protein: NP_002931.2 NP_001035809.1

108773782

NP_002931.2

NM_002940.2

67,314 Da

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the OABP subfamily. Alternatively referred to as the RNase L inhibitor, this protein functions to block the activity of ribonuclease L. Activation of ribonuclease L leads to inhibition of protein synthesis in the 2-5A/RNase L system, the central pathway for viral interferon action. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

0.1 mg

225 USD