Goat anti-CD11A / integrin alpha L Antibody | MyBioSource MBS421988 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

MyBioSource

product type :

antibody

product name :

Goat anti-CD11A / integrin alpha L Antibody

catalog :

MBS421988

quantity :

0.1 mg

price :

290 USD

clonality :

polyclonal

host :

goat

conjugate :

nonconjugated

reactivity :

human, dog

application :

western blot, immunohistochemistry, enzyme immunoassay

product information

catalog number :

MBS421988

products type :

Antibody

products full name :

Goat anti-CD11A / integrin alpha L Antibody

products short name :

CD11A/integrin alpha L

products name syn :

ITGAL; integrin; alpha L (antigen CD11A (p180); lymphocyte function-associated antigen 1; alpha polypeptide); CD11A; LFA-1; LFA1A; LFA-1 alpha; antigen CD11A (p180); lymphocyte function-associated antigen 1; alpha polypeptide; integrin alpha L; integrin gene promoter; lymphocyte function-associated antigen 1; ITGAL; integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide); CD11A; LFA-1; LFA1A; LFA-1 alpha; antigen CD11A (p180), lymphocyte function-associated antigen 1, alpha polypeptide; integrin alpha L; integrin gene promoter; lymphocyte function-associated antigen 1

other names :

integrin alpha-L isoform a; Integrin alpha-L; integrin alpha-L; LFA-1A; LFA-1 alpha; integrin gene promoter; CD11 antigen-like family member A; lymphocyte function-associated antigen 1; leukocyte adhesion glycoprotein LFA-1 alpha chain; leukocyte function-associated molecule 1 alpha chain; antigen CD11A (p180), lymphocyte function-associated antigen 1, alpha polypeptide; integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide); CD11 antigen-like family member A; Leukocyte adhesion glycoprotein LFA-1 alpha chain; LFA-1A; Leukocyte function-associated molecule 1 alpha chain; CD_antigen: CD11a

products gene name :

ITGAL

other gene names :

ITGAL; ITGAL; CD11A; LFA-1; LFA1A; CD11A; LFA-1A

uniprot entry name :

ITAL_HUMAN

clonality :

Polyclonal

host :

Goat

reactivity :

Human, Dog

sequence length :

1170

sequence :

YQVRIQPSIHDHN

purity :

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

form :

Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

concentration :

100ug specific antibody in 200ul

storage stability :

Aliquot and store at -20 degree C. Minimize freezing and thawing.

tested application :

Peptide ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

app notes :

Immunohistochemistry: In paraffin embedded Human Liver shows selected staining of cells within aggregated splenocytes of the white pulp. Recommended concentration, 4-6ug/ml. Western Blot: Approx 200kDa band observed in Human Spleen and Tonsil lysates (calculated MW of 129kDa according to NP_002200.2). The observed molecular weight corresponds to earlier findings with different antibodies from other commercial sources. Recommended concentration: 0.5-2ug/ml. Peptide ELISA: antibody detection limit dilution 1:16000.

other info1 :

Epitope: Internal Region. Immunogen: Peptide with sequence C-YQVRIQPSIHDHN, from the internal region of the protein sequence according to NP_002200.2; NP_001107852.1. Corresponding Immunizing Peptide: Catalog #MBS426430

other info2 :

Important Note: This antibody is expected to recognize both reported isoforms (NP_002200.2; NP_001107852.1).

ncbi gi num :

167466215

ncbi acc num :

NP_002200.2

ncbi gb acc num :

NM_002209.2

ncbi mol weight :

119,224 Da

ncbi pathways :

Adaptive Immune System Pathway 366160!!CXCR3-mediated Signaling Events Pathway 138011!!Cell Adhesion Molecules (CAMs) Pathway 83069!!Cell Adhesion Molecules (CAMs) Pathway 480!!Cell Surface Interactions At The Vascular Wall Pathway 106062!!Epstein-Barr Virus Infection Pathway 585562!!Epstein-Barr Virus Infection Pathway 587115!!Extracellular Matrix Organization Pathway 576262!!Focal Adhesion Pathway 198795!!HTLV-I Infection Pathway 373901

ncbi summary :

ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

size :

0.1 mg

price :

290 USD