catalog number :
MBS421987
products full name :
Goat anti-RAB23 Antibody
products short name :
RAB23
products name syn :
RAB23; RAB23; member RAS oncogene family; RP3-496N17.3; DKFZp781H0695; HSPC137; MGC8900; OTTHUMP00000040021; RAB family small GTP binding protein RAB 23; Ras-related protein Rab-23; RAB23; RAB23, member RAS oncogene family; RP3-496N17.3; DKFZp781H0695; HSPC137; MGC8900; OTTHUMP00000040021; RAB family small GTP binding protein RAB 23; Ras-related protein Rab-23
other names :
ras-related protein Rab-23; Ras-related protein Rab-23; ras-related protein Rab-23; RAB family small GTP binding protein RAB 23; RAB23, member RAS oncogene family
products gene name :
RAB23
other gene names :
RAB23; RAB23; HSPC137
uniprot entry name :
RAB23_HUMAN
reactivity :
Human, Mouse, Rat, Dog
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Western Blot: Approx 30kDa band observed in Mouse Eye lysates (calculated MW of 26.7kDa according to Human NP_057361.3 and 26.8kDa according to Mouse NP_033025.2). The observed molecular weight corresponds to earlier findings with different antibodies from other commercial sources. Recommended concentration: 1-3ug/ml. Recommended concentration: 1-3ug/ml. Peptide ELISA: antibody detection limit dilution 1:64000.
other info1 :
Epitope: C Terminus. Immunogen: Peptide with sequence C-PNKQRTKKNRNP, from the C Terminus of the protein sequence according to NP_057361.3; NP_899050.1. Corresponding Immunizing Peptide: Catalog #MBS425721
other info2 :
Important Note: Both reported variants (NP_057361.3; NP_899050.1) represent identical protein.
ncbi acc num :
NP_057361.3
ncbi gb acc num :
NM_016277.4
ncbi mol weight :
26,659 Da
ncbi pathways :
Hedgehog Signaling Pathway 198835!!Hedgehog Signaling Events Mediated By Gli Proteins Pathway 137912!!Hedgehog Signaling Pathway 83063!!Hedgehog Signaling Pathway 474
ncbi summary :
This gene encodes a small GTPase of the Ras superfamily. Rab proteins are involved in the regulation of diverse cellular functions associated with intracellular membrane trafficking, including autophagy and immune response to bacterial infection. The encoded protein may play a role in central nervous system development by antagonizing sonic hedgehog signaling. Disruption of this gene has been implicated in Carpenter syndrome as well as cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]