catalog number :
MBS421980
products full name :
Goat anti-Lactoperoxidase Antibody
products short name :
Lactoperoxidase
products name syn :
lactoperoxidase; MGC129990; LPO; MGC129991; SPO; salivary peroxidase; lactoperoxidase antibody; MGC129990 antibody; LPO antibody; MGC129991 antibody; SPO antibody; salivary peroxidase antibody; Lactoperoxidase; Lactoperoxidase
other names :
lactoperoxidase isoform 1 preproprotein; Lactoperoxidase; lactoperoxidase; lactoperoxidase; Salivary peroxidase; SPO
other gene names :
LPO; LPO; SPO; SAPX; LPO; SPO
uniprot entry name :
PERL_HUMAN
reactivity :
Tested: Human; Expected from sequence similarity: Human, Mouse, Rat, Pig, Cow
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Peptide ELISA: Antibody detection limit dilution 1: 128000. Western Blot: Approx 70-75kDa band observed in Human Lung lysates (calculated MW of 80.3kDa according to NP_006142.1). Recommended concentration: 0.01-0.03ug/ml.
other info1 :
Immunogen: Peptide with sequence C-KHAKGRTRTAIRN, from the internal region of the protein sequence according to NP_006142.1. Epitope: Internal region
other info2 :
Note: This antibody is expected to recognise isoform 1 (NP_006142.1) only.
ncbi acc num :
NP_006142.1
ncbi gb acc num :
NM_006151.2
ncbi mol weight :
70,984 Da
ncbi pathways :
Salivary Secretion Pathway (153376); Salivary Secretion Pathway (153352)
ncbi summary :
This gene encodes a member of the peroxidase family of proteins. The encoded preproprotein is proteolytically processed to generate the mature enzyme. Following its secretion from salivary, mammary, and other mucosal glands, this enzyme catalyzes the generation of the antimicrobial substance hypothiocyanous acid. This gene is present in a gene cluster on chromosome 17. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. [provided by RefSeq, Jan 2016]
uniprot summary :
LPO: May contribute to airway host defense against infection. Belongs to the peroxidase family. XPO subfamily. Protein type: Secreted; EC 1.11.1.7; Oxidoreductase; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 17q23.1. Cellular Component: basolateral plasma membrane; cytoplasm; extracellular space. Molecular Function: heme binding; metal ion binding. Biological Process: defense response to bacterium; detection of chemical stimulus involved in sensory perception of bitter taste; hydrogen peroxide catabolic process; response to oxidative stress; thiocyanate metabolic process