This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
antibody
product name :
Goat anti-CHN2 Antibody
catalog :
MBS421961
quantity :
0.1 mg
price :
290 USD
clonality :
polyclonal
host :
goat
conjugate :
nonconjugated
reactivity :
human, mouse, dog
application :
western blot, immunohistochemistry, enzyme immunoassay
product information
catalog number :
MBS421961
products type :
Antibody
products full name :
Goat anti-CHN2 Antibody
products short name :
CHN2
products name syn :
CHN2; chimerin (chimaerin) 2; ARHGAP3; RHOGAP3; RhoGAP3; beta chimerin; Chimerin 2 (GTPase-activating protein; rho; 3); BCH; MGC138360; rho-GTPase-activating protein 3; CHN2; chimerin (chimaerin) 2; ARHGAP3; RHOGAP3; RhoGAP3; beta chimerin; Chimerin 2 (GTPase-activating protein, rho, 3); BCH; MGC138360; rho-GTPase-activating protein 3
other names :
beta-chimaerin isoform 1; Beta-chimaerin; beta-chimaerin; beta-chimerin; beta3-chimaerin; chimerin, beta-2; chimerin (chimaerin) 2; chimerin, testis-specific; rho-GTPase-activating protein 3; chimerin 2; Beta-chimerin; Rho GTPase-activating protein 3
products gene name :
CHN2
other gene names :
CHN2; CHN2; BCH; CHN2-3; ARHGAP3; RHOGAP3; ARHGAP3; BCH
uniprot entry name :
CHIO_HUMAN
clonality :
Polyclonal
host :
Goat
reactivity :
Human, Mouse, Dog, Cow
sequence length :
332
sequence :
QILIENEDVLF
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB)
app notes :
Immunohistochemistry: In paraffin embedded Human Cortex shows staining of neuronal bodies. Recommended concentration, 3-6ug/ml. Western Blot: Preliminary experiments in Human Brain (Cerebellum and Frontal Cortex) lysates gave no specific signal but low background (at antibody concentration up to 1ug/ml). Peptide ELISA: antibody detection limit dilution 1:8000.
other info1 :
Epitope: C Terminus. Immunogen: Peptide with sequence C-QILIENEDVLF, from the C Terminus of the protein sequence according to NP_001035025.1; NP_004058.1. Corresponding Immunizing Peptide: Catalog #MBS426432
other info2 :
Important Note: This antibody is expected to recognize both reported isoforms (NP_004058.1; NP_001035025.1).
ncbi gi num :
91106928
ncbi acc num :
NP_001035025.1
ncbi gb acc num :
NM_001039936.2
ncbi mol weight :
62,441 Da
ncbi pathways :
ErbB1 Downstream Signaling Pathway 138057!!Regulation Of RAC1 Activity Pathway 169346!!Rho GTPase Cycle Pathway 106503!!Signal Transduction Pathway 477114!!Signaling By Rho GTPases Pathway 106502
ncbi summary :
This gene encodes a guanosine triphosphate (GTP)-metabolizing protein that contains a phorbol-ester/diacylglycerol (DAG)-type zinc finger, a Rho-GAP domain, and an SH2 domain. The encoded protein translocates from the cytosol to the Golgi apparatus membrane upon binding by diacylglycerol (DAG). Activity of this protein is important in cell proliferation and migration, and expression changes in this gene have been detected in cancers. A mutation in this gene has also been associated with schizophrenia in men. Alternative transcript splicing and the use of alternative promoters results in multiple transcript variants. [provided by RefSeq, May 2014]
size :
0.1 mg
price :
290 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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