Goat anti-FAS / CD95 Antibody | MyBioSource MBS421960 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

MyBioSource

product type :

antibody

product name :

Goat anti-FAS / CD95 Antibody

catalog :

MBS421960

quantity :

0.1 mg

price :

290 USD

clonality :

polyclonal

host :

goat

conjugate :

nonconjugated

reactivity :

human

application :

western blot, enzyme immunoassay

product information

catalog number :

MBS421960

products type :

Antibody

products full name :

Goat anti-FAS / CD95 Antibody

products short name :

FAS/CD95

products name syn :

FAS; Fas (TNF receptor superfamily; member 6); ALPS1A; APO-1; APT1; CD95; FAS1; FASTM; TNFRSF6; APO-1 cell surface antigen; CD95 antigen; Fas AMA; Fas antigen; OTTHUMP00000020045; OTTHUMP00000020046; OTTHUMP00000020051; OTTHUMP00000059646; apoptosis antigen 1; tumor necrosis factor receptor superfamily member 6; tumor necrosis factor receptor superfamily; member 6; FAS; Fas (TNF receptor superfamily, member 6); ALPS1A; APO-1; APT1; CD95; FAS1; FASTM; TNFRSF6; APO-1 cell surface antigen; CD95 antigen; Fas AMA; Fas antigen; OTTHUMP00000020045; OTTHUMP00000020046; OTTHUMP00000020051; OTTHUMP00000059646; apoptosis antigen 1; tumor necrosis factor receptor superfamily member 6; tumor necrosis factor receptor superfamily, member 6

other names :

tumor necrosis factor receptor superfamily member 6 isoform 1; Tumor necrosis factor receptor superfamily member 6; tumor necrosis factor receptor superfamily member 6; Fas AMA; FAS 827dupA; CD95 antigen; FASLG receptor; apoptosis antigen 1; Delta Fas/APO-1/CD95; FAS receptor variant 9; APO-1 cell surface antigen; TNF receptor superfamily member 6; apoptosis-mediating surface antigen FAS; Fas (TNF receptor superfamily, member 6); tumor necrosis factor receptor superfamily, member 6; Fas cell surface death receptor; Apo-1 antigen; Apoptosis-mediating surface antigen FAS; FASLG receptor; CD_antigen: CD95

products gene name :

FAS

other gene names :

FAS; FAS; APT1; CD95; FAS1; APO-1; FASTM; ALPS1A; TNFRSF6; APT1; FAS1; TNFRSF6

uniprot entry name :

TNR6_HUMAN

clonality :

Polyclonal

host :

Goat

reactivity :

Human

sequence length :

335

sequence :

KTCRKHRKENQGSH

purity :

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

form :

Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

concentration :

100ug specific antibody in 200ul

storage stability :

Aliquot and store at -20 degree C. Minimize freezing and thawing.

tested application :

Peptide ELISA (EIA), Western Blot (WB)

app notes :

Western Blot: Approx 37kDa band observed in lysates of cell line MOLT4 (calculated MW of 37.7kDa according to NP_000034.1). Recommended concentration: 0.1-0.3ug/ml. Peptide ELISA: antibody detection limit dilution 1:32000.

other info1 :

Epitope: Internal Region. Immunogen: Peptide with sequence KTCRKHRKENQGSH, from the internal region of the protein sequence according to NP_000034.1; NP_690610.1; NP_690611.1. Corresponding Immunizing Peptide: Catalog #MBS426336

other info2 :

Important Note: This antibody is expected to recognize reported isoforms 1 (NP_000034.1), 2 (NP_690610.1) and 3 (NP_690611.1).

ncbi gi num :

4507583

ncbi acc num :

NP_000034.1

ncbi gb acc num :

NM_000043.4

ncbi mol weight :

24,781 Da

ncbi pathways :

Adipogenesis Pathway 198832!!African Trypanosomiasis Pathway 194384!!African Trypanosomiasis Pathway 194323!!Allograft Rejection Pathway 920963!!Allograft Rejection Pathway 83123!!Allograft Rejection Pathway 535!!Alzheimer's Disease Pathway 83097!!Alzheimer's Disease Pathway 509!!Alzheimers Disease Pathway 672448!!Apoptosis Pathway 198797

ncbi summary :

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains a death domain. It has been shown to play a central role in the physiological regulation of programmed cell death, and has been implicated in the pathogenesis of various malignancies and diseases of the immune system. The interaction of this receptor with its ligand allows the formation of a death-inducing signaling complex that includes Fas-associated death domain protein (FADD), caspase 8, and caspase 10. The autoproteolytic processing of the caspases in the complex triggers a downstream caspase cascade, and leads to apoptosis. This receptor has been also shown to activate NF-kappaB, MAPK3/ERK1, and MAPK8/JNK, and is found to be involved in transducing the proliferating signals in normal diploid fibroblast and T cells. Several alternatively spliced transcript variants have been described, some of which are candidates for nonsense-mediated mRNA decay (NMD). The isoforms lacking the transmembrane domain may negatively regulate the apoptosis mediated by the full length isoform. [provided by RefSeq, Mar 2011]

size :

0.1 mg

price :

290 USD