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company name :
MyBioSource
product type :
antibody
product name :
Goat anti-ATG16L1 Antibody
catalog :
MBS421951
quantity :
0.1 mg
price :
300 USD
clonality :
polyclonal
host :
goat
conjugate :
nonconjugated
reactivity :
human, mouse, rat, dog
application :
western blot, enzyme immunoassay
more info or order :
product information
catalog number :
MBS421951
products type :
Antibody
products full name :
Goat anti-ATG16L1 Antibody
products short name :
ATG16L1
products name syn :
ATG16; autophagy related 16-like 1 (S. cerevisiae); hCG_1817841; APG16L; ATG16L; FLJ00045; FLJ10035; FLJ10828; FLJ22677; WDR30; APG16 autophagy 16-like; APG16L beta; ATG16 autophagy related 16-like protein 1; WD repeat domain 30; ATG16 antibody; autophagy related 16-like 1 (S. cerevisiae) antibody; hCG_1817841 antibody; APG16L antibody; ATG16L antibody; FLJ00045 antibody; FLJ10035 antibody; FLJ10828 antibody; FLJ22677 antibody; WDR30 antibody; APG16 autophagy 16-like antibody; APG16L beta antibody; ATG16 autophagy related 16-like protein 1 antibody; WD repeat domain 30 antibody
other names :
autophagy-related protein 16-1 isoform 1; Autophagy-related protein 16-1; autophagy-related protein 16-1; autophagy related 16 like 1; APG16-like 1
products gene name :
ATG16L1
other gene names :
ATG16L1; ATG16L1; IBD10; WDR30; APG16L; ATG16A; ATG16L; APG16L
uniprot entry name :
A16L1_HUMAN
clonality :
Polyclonal
host :
Goat
reactivity :
Tested: Mouse; Expected from sequence similarity: Human, Mouse, Rat, Dog
sequence length :
607
sequence :
KVEKVLSKQHSSSIN
purity :
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
form :
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
concentration :
100ug specific antibody in 200ul
storage stability :
Aliquot and store at -20 degree C. Minimize freezing and thawing.
tested application :
Peptide ELISA (EIA), Western Blot (WB)
app notes :
Peptide ELISA: Antibody detection limit dilution 1: 32000. Western Blot: Approx 65kDa band observed in Mouse Brain lysates (calculated MW of 68.1kDa according to Mouse NP_084122.2). Recommended concentration: 0. 01-0.1ug/ml.
other info1 :
Immunogen: Peptide with sequence C-KVEKVLSKQHSSSIN, from the internal region (near the C Terminus) of the protein sequence according to NP_110430.5; NP_060444.3. Epitope: Internal region (near the C Terminus)
other info2 :
Note: This antibody is expected to recognise both reported isoforms (NP_110430.5 and NP_060444.3).
ncbi gi num :
124256480
ncbi acc num :
NP_110430.5
ncbi gb acc num :
NM_030803.6
ncbi mol weight :
49,486 Da
ncbi pathways :
Cellular Responses To Stress Pathway (1270414); Macroautophagy Pathway (1270432); Regulation Of Autophagy Pathway (83058); Regulation Of Autophagy Pathway (468); Senescence And Autophagy Pathway (198780)
ncbi summary :
The protein encoded by this gene is part of a large protein complex that is necessary for autophagy, the major process by which intracellular components are targeted to lysosomes for degradation. Defects in this gene are a cause of susceptibility to inflammatory bowel disease type 10 (IBD10). Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jun 2010]
uniprot summary :
ATG16L1: Plays an essential role in autophagy. Homooligomer. Interacts with ATG5. Part of either the minor and major complexes respectively composed of 4 sets of ATG12-ATG5 and ATG16L1 (400 kDa) or 8 sets of ATG12-ATG5 and ATG16L1 (800 kDa). Belongs to the WD repeat ATG16 family. 5 isoforms of the human protein are produced by alternative splicing. Protein type: Adaptor/scaffold; Membrane protein, peripheral; Autophagy. Chromosomal Location of Human Ortholog: 2q37.1. Cellular Component: autophagic vacuole; axoneme; cytosol; pre-autophagosomal structure membrane. Molecular Function: identical protein binding; protein binding; small conjugating protein ligase activity. Biological Process: autophagic vacuole formation; macroautophagy; protein homooligomerization; protein transport. Disease: Inflammatory Bowel Disease 10
size1 :
0.1 mg
price1 :
300 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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